S-acetyl-PEG-Acid contains a carboxylic acid functional group (-COOH) attached to the end of a PEG chain via a thioether linkage.
The carboxylic acid functional group of S-acetyl-PEG-Acid can be utilized for the conjugation of various molecules, such as drugs, peptides, and proteins, through amide bond formation. The resulting conjugates exhibit improved pharmacokinetic and pharmacodynamic properties, including increased solubility, stability, and bioavailability.
S-acetyl-PEG-Acid can also be employed as a surface modifier for biomedical applications. For instance, it can be covalently attached to the surface of medical devices or implants to improve biocompatibility and reduce immune response. Additionally, the thioether linkage in S-acetyl-PEG-Acid provides an anchoring point for other functional groups, enabling further modification and optimization of the compound for specific applications.