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Phosphoramidites drive oligonucleotide synthesis by enabling precise, efficient construction of custom DNA or RNA sequences. They provide high coupling efficiency and selective protection, making them ideal for nucleic acid research, gene synthesis, and therapeutic development.

phosphoramidite

Cat# Name Structure M.W. Purity Pricing
AP13768SIMA phosphoramidite, 6-isomer (hydroxyprolinol)1480.52≥95% Pricing
AP15325DMT-dA(bz) Phosphoramidite857.93≥95% Pricing
AP15327DMT-2'O-Methyl-rU Phosphoramidite760.81≥95% Pricing
AP153293'-TBDMS-Bz-rA Phosphoramidite988.19≥97% Pricing
AP15337IBU-DC Phosphoramidite799.89≥95% Pricing
AP15338I-bu-rG Phosphoramidite970.18≥95 Pricing
AP153392'-F-Bz-dC Phosphoramidite851.9≥98% Pricing
AP15342N2-iBu-5’-O-DMTr-2’-O-propargylguanosine-3’-CED-phosphoramidite893.96≥97% Pricing
AP153462'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite772.8≥95% Pricing
AP15351N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite1080.4≥98% Pricing
AP15353N6-Bz-5’-O-DMTr-2’-O-hexadecanyl adenosine 3’-CED phosphoramidite1098.4≥98% Pricing
AP15354Sacituzumab govitecan (solution)842.89≥97% Pricing
AP153752-O-DMT-Sulfonyldiethanol phosphoramidite656.77≥97% Pricing
AP15377N6-Methyl-dA phosphoramidite767.9≥98% Pricing
AP15379Amino-Modifier C6 dT995.03≥97% Pricing
AP15406DBCO-TEG phosphoramidite708.84≥NMR 1H and 31P (95 %) Pricing
AP13733Abasic phosphoramidite193.16≥95% Pricing
AP14129Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite344.39≥95% Pricing
AP13741Alkyne Phosphoramidite, 5'-terminal409.50≥95% Pricing
AP13807TFA-aminolinker C6 phosphoramidite413.42≥95% Pricing
AP13742Alkyne-PEG4-phosphoramidite432.49≥95% Pricing
AP15586TCO phosphoramidite C6469.61≥95% Pricing
AP13804endo-BCN CE-Phosphoramidite481.57≥95% Pricing
AP14128TBDMS-PEG5-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite508.7≥95% Pricing
AP15368Spacer phosphoramidite C3578.68≥98% Pricing
AP15361MMT-Hexylaminolinker Phosphoramidite589.75≥98% Pricing
AP13794DusQ1 amidite, 5'-terminal676.75≥95% Pricing
AP14248DMS(O)MT aminolink C6681.86≥95% Pricing
AP14530(S)-T-GNA phosphoramidite702.80≥95% Pricing
AP13739Alkyne Amidite, hydroxyprolinol713.84≥95% Pricing
AP13786Chemical phosphorylation reagent722.80≥95% Pricing
AP12918TAMRA phosphoramidite, 5-isomer727.83≥ (95%), coupling test Pricing
AP15587TAMRA phosphoramidite, 6-isomer727.83≥95% Pricing
AP13793dU (Deoxyuridine) phosphoramidite730.79≥95% Pricing
AP15340DMT-dT Phosphoramidite744.81≥97% Pricing
AP15323DMT-2′Fluoro-dU Phosphoramidite748.78≥95% Pricing
AP153555'-DMT-5-F-2'-dU Phosphoramidite748.8≥98% Pricing
AP153635-ETHYNYL-DU CEP754.8≥97 Pricing
AP15362Inosine (dI) phosphoramidite754.81≥97% Pricing
AP153053'-O-DMTr-thymidine 5'-CE phosphoramidite760.81≥95% Pricing
AP153595-Methyl-2'-Fluoro-U Phosphoramidite762.8≥97% Pricing
AP15306DMT-dC(ac) Phosphoramidite771.84≥95% Pricing
AP153452'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite784.84≥98% Pricing
AP14075Hexaethylene glycol phosphoramidite784.92≥95% Pricing
AP15343Ac-dA Phosphoramidite795.86≥97% Pricing
AP153525'-O-DMTr-2'-O-methyl-N6-methyl adenosine 3'-CED phosphoramidite797.9≥98% Pricing
AP153762'-OMe-Ac-C Phosphoramidite801.86≥95% Pricing
AP153282’-O-MOE-U-3’-phosphoramidite804.86≥95% Pricing
AP12728Cyanine5 phosphoramidite816.49≥, 31P, (80%) Pricing
AP15313DMT-dG(dmf) Phosphoramidite824.90≥98% Pricing
AP15371DMT-dC(bz) Phosphoramidite833.9≥98% Pricing
AP153603-Cyanovinylcarbazole phosphoramidite837≥98% Pricing
AP15326DMT-dG(ib) Phosphoramidite839.92≥99% Pricing
AP13838Cyanine3 phosphoramidite, 5'-terminal841.81≥95% Pricing
AP12896FAM Phosphoramidite, 6-Isomer843.94≥ 31P, (95+%), isomeric purity > 97% Pricing
AP10674DMT-Biotin-C6 Phosphoramidite847.06≥95% Pricing
AP15330DMT-5Me-dC(Bz)-CE Phosphoramidite847.93≥95% Pricing
AP153442'-OMe-dmf-G-CE-Phosphoramidite854.93≥98% Pricing
AP15341DMT-2'Fluoro-DG(IB) Amidite857.91≥98% Pricing
AP153242'-O-Me-C(Bz) Phosphoramidite863.93≥95% Pricing
AP15370DMTr-LNA-G(iBu)-3’-CED-phosphoramidite867.9≥95% Pricing
AP153222'-OMe-G(ibu) Phosphoramidite869.94≥95% Pricing
AP15367DMTr-LNA-5MeC(Bz)-3-CED-phosphoramidite876≥97% Pricing
AP13777Alkyne dT phosphoramidite877.96≥95% Pricing
AP15366DMT-2'-OME-dC(Bz)-CE-Phosphoramidite877.96≥97% Pricing
AP10672DMTR-biotin-PEG3-(2-cyanoethyl) diisopropylphosphoramidite878.07≥95% Pricing
AP15378TFA-aminoallyl-2'-deoxyuridine Phosphoramidite881.87≥97% Pricing
AP153745'-ODMT cEt G Phosphoramidite881.95≥95% Pricing
AP153722'-OMe-A(Bz) Phosphoramidite887.96≥97% Pricing
AP15373DMT-dA(PAc) Phosphoramidite887.96≥95% Pricing
AP153582’-O-MOE-C(Bz)-3’-phosphoramidite908≥95% Pricing
AP145315'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite914.00≥95% Pricing
AP12738Cyanine5.5 phosphoramidite, 5'-terminal916.61≥, 31P, (85%) Pricing
AP12904R6G phosphoramidite, 6-isomer949.92≥ 31P, (95+%), isomeric purity > 97% Pricing
AP15369DMT-2'O-Methyl-rC(tac) Phosphoramidite950.07≥98% Pricing
AP15331Cyanine 3 Phosphoramidite953.64≥95% Pricing
AP12934Pyrene phosphoramidite dU955.04≥ (95%), 31P, Pricing
AP13782Biotin phosphoramidite (hydroxyprolinol)959.18≥95% Pricing
AP15335Bz-rC Phosphoramidite964.17≥95% Pricing
AP153123'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine 2'-CE phosphoramidite970.18≥98% Pricing
AP12908JOE phosphoramidite, 6-isomer972.88≥95% Pricing
AP12907JOE phosphoramidite, 5-isomer972.88≥, 31P, (95%), functional testing Pricing
AP13805TET phosphoramidite, 6-isomer981.72≥95% Pricing
AP15336Bz-rA Phosphoramidite988.19≥97% Pricing
AP14072DusQ1 phosphoramidite995.11≥95% Pricing
AP13801DusQ2 phosphoramidite997.08≥95% Pricing
AP13812Perylene dU phosphoramidite1005.10≥95% Pricing
AP13808VIC phosphoramidite, 6-isomer1023.39≥95% Pricing
AP12944HEX phosphoramidite, 6-isomer1050.61≥95% Pricing
AP13767SIMA phosphoramidite, 6-isomer1065.02≥95% Pricing
AP13797DusQ1 dT phosphoramidite1411.58≥95% Pricing
AP13800DusQ2 dT phosphoramidite1413.55≥95% Pricing
AP14085Long trebler phosphoramidite1475.78≥95% Pricing
AP14083SIMA-dT phosphoramidite, 6-isomer1646.67≥95% Pricing

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    Phosphoramidite Overview

    Phosphoramidites are essential building blocks in oligonucleotide synthesis, driving the creation of custom DNA or RNA sequences. They feature a reactive phosphate group, enabling precise stepwise addition of nucleotides. This method ensures efficient and controlled synthesis in various research and therapeutic applications.

    Key Features:

    • Reactive Phosphate Group: Enables efficient bonding in nucleic acid synthesis.
    • High Coupling Efficiency: Ensures rapid and precise nucleotide addition.
    • Selective Protection: Uses 5′-O-DMTr to control reactions, preventing unwanted outcomes.

    Applications:

    • Oligonucleotide Synthesis: Ideal for producing custom DNA or RNA strands.
    • Therapeutic Development: Crucial for designing antisense oligonucleotides and siRNA.
    • Gene Synthesis: Helps construct synthetic genes for research and therapies.

    Advantages:

    • Precision: Facilitates highly controlled synthesis of nucleotides.
    • Versatility: Suitable for both DNA and RNA, with room for modifications.

    Phosphoramidites offer researchers in nucleic acid research and therapeutic development a reliable, high-precision method for synthesizing custom oligonucleotides.