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Phosphoramidites drive oligonucleotide synthesis by enabling precise, efficient construction of custom DNA or RNA sequences. They provide high coupling efficiency and selective protection, making them ideal for nucleic acid research, gene synthesis, and therapeutic development.

phosphoramidite

Cat# Name Structure M.W. Purity Pricing
AP13768SIMA phosphoramidite, 6-isomer (hydroxyprolinol)
Quick viewSIMA phosphoramidite, 6-isomer (hydroxyprolinol)
1480.52≥95% Pricing
AP15325DMT-dA(bz) Phosphoramidite
Quick viewDMT-dA(bz) Phosphoramidite
857.93≥95% Pricing
AP15327DMT-2'O-Methyl-rU Phosphoramidite
Quick viewDMT-2'O-Methyl-rU Phosphoramidite
760.81≥95% Pricing
AP153293'-TBDMS-Bz-rA Phosphoramidite
Quick view3'-TBDMS-Bz-rA Phosphoramidite
988.19≥97% Pricing
AP15337IBU-DC Phosphoramidite
Quick viewIBU-DC Phosphoramidite
799.89≥95% Pricing
AP15338I-bu-rG Phosphoramidite
Quick viewI-bu-rG Phosphoramidite
970.18≥95 Pricing
AP153392'-F-Bz-dC Phosphoramidite
Quick view2'-F-Bz-dC Phosphoramidite
851.9≥98% Pricing
AP15342N2-iBu-5’-O-DMTr-2’-O-propargylguanosine-3’-CED-phosphoramidite
Quick viewN2-iBu-5’-O-DMTr-2’-O-propargylguanosine-3’-CED-phosphoramidite
893.96≥97% Pricing
AP153462'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite
Quick view2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite
772.8≥95% Pricing
AP15351N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite
Quick viewN2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite
1080.4≥98% Pricing
AP15353N6-Bz-5’-O-DMTr-2’-O-hexadecanyl adenosine 3’-CED phosphoramidite
Quick viewN6-Bz-5’-O-DMTr-2’-O-hexadecanyl adenosine 3’-CED phosphoramidite
1098.4≥98% Pricing
AP15354Sacituzumab govitecan (solution)
Quick view
842.89≥97% Pricing
AP153752-O-DMT-Sulfonyldiethanol phosphoramidite
Quick view2-O-DMT-Sulfonyldiethanol phosphoramidite
656.77≥97% Pricing
AP15377N6-Methyl-dA phosphoramidite
Quick viewN6-Methyl-dA phosphoramidite
767.9≥98% Pricing
AP15379Amino-Modifier C6 dT
Quick viewAmino-Modifier C6 dT
995.03≥97% Pricing
AP15406DBCO-TEG phosphoramidite
Quick viewDBCO-TEG phosphoramidite
708.84≥NMR 1H and 31P (95 %) Pricing
AP13733Abasic phosphoramidite
Quick viewAbasic phosphoramidite
193.16≥95% Pricing
AP14129Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite
Quick viewPropargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite
344.39≥95% Pricing
AP13741Alkyne Phosphoramidite, 5'-terminal
Quick viewAlkyne Phosphoramidite, 5'-terminal
409.50≥95% Pricing
AP13807TFA-aminolinker C6 phosphoramidite
Quick viewTFA-aminolinker C6 phosphoramidite
413.42≥95% Pricing
AP13742Alkyne-PEG4-phosphoramidite
Quick viewAlkyne-PEG4-phosphoramidite
432.49≥95% Pricing
AP13804endo-BCN CE-Phosphoramidite
Quick viewendo-BCN CE-Phosphoramidite
481.57≥95% Pricing
AP14128TBDMS-PEG5-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite
Quick viewTBDMS-PEG5-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite
508.7≥95% Pricing
AP15368Spacer phosphoramidite C3
Quick viewSpacer phosphoramidite C3
578.68≥98% Pricing
AP15361MMT-Hexylaminolinker Phosphoramidite
Quick viewMMT-Hexylaminolinker Phosphoramidite
589.75≥98% Pricing
AP13794DusQ1 amidite, 5'-terminal
Quick viewDusQ1 amidite, 5'-terminal
676.75≥95% Pricing
AP14248DMS(O)MT aminolink C6
Quick viewDMS(O)MT aminolink C6
681.86≥95% Pricing
AP14530(S)-T-GNA phosphoramidite
Quick view(S)-T-GNA phosphoramidite
702.80≥95% Pricing
AP13739Alkyne Amidite, hydroxyprolinol
Quick viewAlkyne Amidite, hydroxyprolinol
713.84≥95% Pricing
AP13786Chemical phosphorylation reagent
Quick viewChemical phosphorylation reagent
722.80≥95% Pricing
AP12918TAMRA phosphoramidite, 5-isomer
Quick viewTAMRA phosphoramidite, 5-isomer
727.83≥ (95%), coupling test Pricing
AP13793dU (Deoxyuridine) phosphoramidite
Quick viewdU (Deoxyuridine) phosphoramidite
730.79≥95% Pricing
AP15340DMT-dT Phosphoramidite
Quick viewDMT-dT Phosphoramidite
744.81≥97% Pricing
AP15323DMT-2′Fluoro-dU Phosphoramidite
Quick viewDMT-2′Fluoro-dU Phosphoramidite
748.78≥95% Pricing
AP153555'-DMT-5-F-2'-dU Phosphoramidite
Quick view5'-DMT-5-F-2'-dU Phosphoramidite
748.8≥98% Pricing
AP153635-ETHYNYL-DU CEP
Quick view5-ETHYNYL-DU CEP
754.8≥97 Pricing
AP15362Inosine (dI) phosphoramidite
Quick viewInosine (dI) phosphoramidite
754.81≥97% Pricing
AP153053'-O-DMTr-thymidine 5'-CE phosphoramidite
Quick view3'-O-DMTr-thymidine 5'-CE phosphoramidite
760.81≥95% Pricing
AP153595-Methyl-2'-Fluoro-U Phosphoramidite
Quick view5-Methyl-2'-Fluoro-U Phosphoramidite
762.8≥97% Pricing
AP15306DMT-dC(ac) Phosphoramidite
Quick viewDMT-dC(ac) Phosphoramidite
771.84≥95% Pricing
AP153452'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite
Quick view2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite
784.84≥98% Pricing
AP14075Hexaethylene glycol phosphoramidite
Quick viewHexaethylene glycol phosphoramidite
784.92≥95% Pricing
AP15343Ac-dA Phosphoramidite
Quick viewAc-dA Phosphoramidite
795.86≥97% Pricing
AP153525'-O-DMTr-2'-O-methyl-N6-methyl adenosine 3'-CED phosphoramidite
Quick view5'-O-DMTr-2'-O-methyl-N6-methyl adenosine 3'-CED phosphoramidite
797.9≥98% Pricing
AP153762'-OMe-Ac-C Phosphoramidite
Quick view2'-OMe-Ac-C Phosphoramidite
801.86≥95% Pricing
AP153282’-O-MOE-U-3’-phosphoramidite
Quick view2’-O-MOE-U-3’-phosphoramidite
804.86≥95% Pricing
AP12728Cyanine5 phosphoramidite
Quick viewCyanine5 phosphoramidite
816.49≥, 31P, (80%) Pricing
AP15313DMT-dG(dmf) Phosphoramidite
Quick viewDMT-dG(dmf) Phosphoramidite
824.90≥98% Pricing
AP15371DMT-dC(bz) Phosphoramidite
Quick viewDMT-dC(bz) Phosphoramidite
833.9≥98% Pricing
AP153603-Cyanovinylcarbazole phosphoramidite
Quick view3-Cyanovinylcarbazole phosphoramidite
837≥98% Pricing
AP15326DMT-dG(ib) Phosphoramidite
Quick viewDMT-dG(ib) Phosphoramidite
839.92≥99% Pricing
AP13838Cyanine3 phosphoramidite, 5'-terminal
Quick viewCyanine3 phosphoramidite, 5'-terminal
841.81≥95% Pricing
AP12896FAM Phosphoramidite, 6-Isomer
Quick viewFAM Phosphoramidite, 6-Isomer
843.94≥ 31P, (95+%), isomeric purity > 97% Pricing
AP10674DMT-Biotin-C6 Phosphoramidite
Quick viewDMT-Biotin-C6 Phosphoramidite
847.06≥95% Pricing
AP15330DMT-5Me-dC(Bz)-CE Phosphoramidite
Quick viewDMT-5Me-dC(Bz)-CE Phosphoramidite
847.93≥95% Pricing
AP153442'-OMe-dmf-G-CE-Phosphoramidite
Quick view2'-OMe-dmf-G-CE-Phosphoramidite
854.93≥98% Pricing
AP15341DMT-2'Fluoro-DG(IB) Amidite
Quick viewDMT-2'Fluoro-DG(IB) Amidite
857.91≥98% Pricing
AP153242'-O-Me-C(Bz) Phosphoramidite
Quick view2'-O-Me-C(Bz) Phosphoramidite
863.93≥95% Pricing
AP15370DMTr-LNA-G(iBu)-3’-CED-phosphoramidite
Quick viewDMTr-LNA-G(iBu)-3’-CED-phosphoramidite
867.9≥95% Pricing
AP153222'-OMe-G(ibu) Phosphoramidite
Quick view2'-OMe-G(ibu) Phosphoramidite
869.94≥95% Pricing
AP15367DMTr-LNA-5MeC(Bz)-3-CED-phosphoramidite
Quick viewDMTr-LNA-5MeC(Bz)-3-CED-phosphoramidite
876≥97% Pricing
AP13777Alkyne dT phosphoramidite
Quick viewAlkyne dT phosphoramidite
877.96≥95% Pricing
AP15366DMT-2'-OME-dC(Bz)-CE-Phosphoramidite
Quick viewDMT-2'-OME-dC(Bz)-CE-Phosphoramidite
877.96≥97% Pricing
AP10672DMTR-biotin-PEG3-(2-cyanoethyl) diisopropylphosphoramidite
Quick viewDMTR-biotin-PEG3-(2-cyanoethyl) diisopropylphosphoramidite
878.07≥95% Pricing
AP15378TFA-aminoallyl-2'-deoxyuridine Phosphoramidite
Quick viewTFA-aminoallyl-2'-deoxyuridine Phosphoramidite
881.87≥97% Pricing
AP153745'-ODMT cEt G Phosphoramidite
Quick view5'-ODMT cEt G Phosphoramidite
881.95≥95% Pricing
AP153722'-OMe-A(Bz) Phosphoramidite
Quick view2'-OMe-A(Bz) Phosphoramidite
887.96≥97% Pricing
AP15373DMT-dA(PAc) Phosphoramidite
Quick viewDMT-dA(PAc) Phosphoramidite
887.96≥95% Pricing
AP153582’-O-MOE-C(Bz)-3’-phosphoramidite
Quick view2’-O-MOE-C(Bz)-3’-phosphoramidite
908≥95% Pricing
AP145315'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite
Quick view5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite
914.00≥95% Pricing
AP12738Cyanine5.5 phosphoramidite, 5'-terminal
Quick viewCyanine5.5 phosphoramidite, 5'-terminal
916.61≥, 31P, (85%) Pricing
AP12904R6G phosphoramidite, 6-isomer
Quick viewR6G phosphoramidite, 6-isomer
949.92≥ 31P, (95+%), isomeric purity > 97% Pricing
AP15369DMT-2'O-Methyl-rC(tac) Phosphoramidite
Quick viewDMT-2'O-Methyl-rC(tac) Phosphoramidite
950.07≥98% Pricing
AP15331Cyanine 3 Phosphoramidite
Quick viewCyanine 3 Phosphoramidite
953.64≥95% Pricing
AP12934Pyrene phosphoramidite dU
Quick viewPyrene phosphoramidite dU
955.04≥ (95%), 31P, Pricing
AP13782Biotin phosphoramidite (hydroxyprolinol)
Quick viewBiotin phosphoramidite (hydroxyprolinol)
959.18≥95% Pricing
AP15335Bz-rC Phosphoramidite
Quick viewBz-rC Phosphoramidite
964.17≥95% Pricing
AP153123'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine 2'-CE phosphoramidite
Quick view3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine 2'-CE phosphoramidite
970.18≥98% Pricing
AP12908JOE phosphoramidite, 6-isomer
Quick viewJOE phosphoramidite, 6-isomer
972.88≥95% Pricing
AP12907JOE phosphoramidite, 5-isomer
Quick viewJOE phosphoramidite, 5-isomer
972.88≥, 31P, (95%), functional testing Pricing
AP13805TET phosphoramidite, 6-isomer
Quick viewTET phosphoramidite, 6-isomer
981.72≥95% Pricing
AP15336Bz-rA Phosphoramidite
Quick viewBz-rA Phosphoramidite
988.19≥97% Pricing
AP14072DusQ1 phosphoramidite
Quick viewDusQ1 phosphoramidite
995.11≥95% Pricing
AP13801DusQ2 phosphoramidite
Quick viewDusQ2 phosphoramidite
997.08≥95% Pricing
AP13812Perylene dU phosphoramidite
Quick viewPerylene dU phosphoramidite
1005.10≥95% Pricing
AP13808VIC phosphoramidite, 6-isomer
Quick viewVIC phosphoramidite, 6-isomer
1023.39≥95% Pricing
AP12944HEX phosphoramidite, 6-isomer
Quick viewHEX phosphoramidite, 6-isomer
1050.61≥95% Pricing
AP13767SIMA phosphoramidite, 6-isomer
Quick viewSIMA phosphoramidite, 6-isomer
1065.02≥95% Pricing
AP13797DusQ1 dT phosphoramidite
Quick viewDusQ1 dT phosphoramidite
1411.58≥95% Pricing
AP13800DusQ2 dT phosphoramidite
Quick viewDusQ2 dT phosphoramidite
1413.55≥95% Pricing
AP14085Long trebler phosphoramidite
Quick viewLong trebler phosphoramidite
1475.78≥95% Pricing
AP14083SIMA-dT phosphoramidite, 6-isomer
Quick viewSIMA-dT phosphoramidite, 6-isomer
1646.67≥95% Pricing

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    Phosphoramidite Overview

    Phosphoramidites are essential building blocks in oligonucleotide synthesis, driving the creation of custom DNA or RNA sequences. They feature a reactive phosphate group, enabling precise stepwise addition of nucleotides. This method ensures efficient and controlled synthesis in various research and therapeutic applications.

    Key Features:

    • Reactive Phosphate Group: Enables efficient bonding in nucleic acid synthesis.
    • High Coupling Efficiency: Ensures rapid and precise nucleotide addition.
    • Selective Protection: Uses 5′-O-DMTr to control reactions, preventing unwanted outcomes.

    Applications:

    • Oligonucleotide Synthesis: Ideal for producing custom DNA or RNA strands.
    • Therapeutic Development: Crucial for designing antisense oligonucleotides and siRNA.
    • Gene Synthesis: Helps construct synthetic genes for research and therapies.

    Advantages:

    • Precision: Facilitates highly controlled synthesis of nucleotides.
    • Versatility: Suitable for both DNA and RNA, with room for modifications.

    Phosphoramidites offer researchers in nucleic acid research and therapeutic development a reliable, high-precision method for synthesizing custom oligonucleotides.