2′-OMe-dmf-G-CE-Phosphoramidite

2′-OMe-dmf-G-CE Phosphoramidite (CAS 128219-77-2), a nucleoside amidite analog, contains 2′-O-methyl-dimethoxytrityl (DMF) guanosine and a 5′-O-dimethoxytrityl (DMT) cytidine protecting group. This phosphoramidite supports RNA oligonucleotide synthesis by increasing RNA stability and resisting enzymatic degradation. The dmf group protects the exocyclic amine of guanosine, allowing precise incorporation during solid-phase synthesis.

Key Features:

• CAS Number: 128219-77-2
• Composition: 2′-O-methyl guanosine with dmf and DMT protecting groups
• Function: Builds stable RNA oligonucleotides
• Protection Groups: dmf on guanosine’s exocyclic amine and DMT on the 5′-O position
• Applications:
  • RNA oligonucleotide synthesis
  • Boosts RNA stability for research, diagnostics, and therapeutic development

2′-OMe-dmf-G-CE Phosphoramidite boosts RNA stability and enables efficient oligonucleotide synthesis, making it ideal for genetic research and therapeutic applications.