Aminooxy PEG TCO linkers have an aminooxy moiety on one end and a TCO group on the other. The aminooxy group readily reacts with aldehyde groups of biomolecules. The TCO group on the other end reacts with tetrazine group in a ultrafast and highly specific fashion.
Linkers with aminooxy and TCO combination are ideal for ADC conjugation of sugar modified biomolecules.
