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A proteolysis targeting chimera (PROTAC) is capable of removing specific unwanted proteins. It is a heterobifunctional small molecule composed of two active domains and a linker.

A PROTAC works by inducing selective intracellular proteolysis. One of the two covalently linked protein-binding molecules engages an E3 ubiquitin ligase, and another binds to a target protein to undergo degradation.

Catalog# Name Structure M.W. Purity Pricing
PROTAC
AP12334Thalidomide-O-PEG4-Propargyl488.49≥95% Pricing
AP12127Thalidomide-O-amido-PEG4-propargyl545.55≥95% Pricing
AP12199D-Amino-PEG6-Thalidomide TFA salt565.62≥95% Pricing
AP11051N-(Azido-PEG4)-biocytin645.77≥95% Pricing
AP11060N-(Propargyl-PEG4)-biocytin614.76≥95% Pricing
AP11080D-Biotin-PEG6-Thalidomide791.91≥95% Pricing
AP11087Fmoc-Lys (biotin-PEG4)-OH842.02≥95% Pricing
AP121224-Hydroxy-thalidomide274.23≥95% Pricing
AP12123Thalidomide-Acid332.27≥95% Pricing
AP12124Thalidomide-O-PEG4-Amine493.51≥95% Pricing
AP11576Thalidomide-O-PEG4-Azide519.51≥95% Pricing
AP12125Thalidomide-O-amido-PEG4-azide576.56≥95% Pricing
AP12126Thalidomide-O-PEG4-NHS ester619.58≥95% Pricing
AP12128Thalidomide-O-PEG4-t-butyl ester578.62≥95% Pricing
AP121294-Fluoro-thalidomide276.22≥95% Pricing
AP12130Pomalidomide-PEG4-Azide518.53≥95% Pricing
AP12131VHL Ligand 1 HCl salt467.03≥95% Pricing
AP12132(S,R. S)-AHPC-PEG2-acid618.75≥95% Pricing
AP12133(S,R. S)-AHPC-PEG2-amine hydrochloride salt575.73≥95% Pricing
AP12134(S,R. S)-AHPC-PEG4-amine hydrochloride salt663.83≥95% Pricing
AP12135(S,R. S)-AHPC-PEG4-Azide703.86≥95% Pricing