Pomalidomide-PEG-Azide contains a Pomalidomide moiety, a PEG linker, and an Azide functional group (-N3) attached to the end of the PEG chain. The Azide group is known for its ability to react with other molecules through click chemistry.
Pomalidomide-PEG-Azide has been extensively utilized in the development of novel drug delivery systems, such as targeted drug conjugates and bioconjugates. Its unique chemical properties allow for the efficient conjugation of targeting moieties or other therapeutic agents to the PEG chain via click chemistry. The resulting conjugates exhibit improved stability, increased specificity, and enhanced therapeutic efficacy.
Pomalidomide-PEG-Azide has also been employed as a tool for drug discovery and development. It can be used to screen for potential drug targets or to study the biological effects of small molecules on cells or tissues.