2-(2,6-Dioxopiperidin-3-Yl)-5,6-Difluoroisoindoline-1,3-Dione

2-(2,6-dioxopiperidin-3-yl)-5,6-difluoroisoindole-1,3-dione is a Thalidomide-based cereblon ligand for the recruitment of CRBN proteins. 2-(2,6-dioxopiperidin-3-yl)-5,6-difluoroisoindole-1,3-dione can be linked to protein ligands through linkers to form PROTAC.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.