SGC-CBP30 is a potent CREBBP/EP300 inhibitor with IC50s of 21 nM and 38 nM, respectively, in cell-free assays. The selectivity for CBP is 40-fold and 250-fold higher than the first BRD for BRD4 (BRD4(1)) and BRD4(2), respectively. SGC-CBP30 accelerates FRAP recovery in cells at a concentration of 1 μM.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.