Pomalidomide-PEG4-Azide is a protein degrader builiding block. It is used in the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand, a PEGylated spacer and a terminal azide for click chemistry with a target ligand.
Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.