I-BRD9 is a bromodomain-containing protein, and I-BRD9 is a potent and selective BRD9 inhibitor (pIC 50 = 7.3). Selectivity for BRD9 over 34 other bromodomains and over 700-fold selectivity for the BET family. I-BRD9 is the first selective cytochemical probe for bromodomain-containing protein 9 (BRD9). I-BRD9 was identified by structure-based design and is 200-fold higher than the highly homologous bromodomain-containing protein 7 (BRD7).
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