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DSPE-PEG-SH is a commonly used compound in pharmaceutical research and development. It is a conjugate of three distinct functional groups: DSPE, PEG, and SH. DSPE, or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine, is a phospholipid that is commonly used in drug delivery systems. PEG, or polyethylene glycol, is a hydrophilic polymer that is often used to improve the solubility and bioavailability of drugs. SH, or thiol, is a functional group that can react with other molecules through disulfide bonds.

The combination of these three functional groups in DSPE-PEG-SH allows for a range of applications in pharmaceutical research and development. The DSPE component allows for the conjugation of the compound with liposomes, which are commonly used as drug delivery systems. The PEG component can improve the stability and pharmacokinetics of the liposomes, while the SH group allows for the conjugation of other molecules, such as targeting ligands or imaging agents.

In pharmaceutical research and development, DSPE-PEG-SH is often used to create targeted drug delivery systems. By conjugating targeting ligands to the SH group, drugs can be delivered specifically to cells or tissues of interest. Additionally, the PEG component can increase the circulation time of the liposomes, allowing for sustained drug release and improved therapeutic efficacy.

DSPE-PEG-SH is a versatile compound that has many potential applications in pharmaceutical research and development. Its unique combination of functional groups allows for the creation of targeted drug delivery systems with improved pharmacokinetics and therapeutic efficacy.


Cat# Name Structure M.W. Purity Pricing
AP13632DSPE-PEG-SH, MW 1K1000≥95% Pricing
AP13662DSPE-PEG-SH, MW 2K2000≥95% Pricing
AP13677DSPE-PEG-SH, MW 3.4K3400≥95% Pricing
AP13687DSPE-PEG-SH, MW 5K5000≥95% Pricing

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