Folate PEG

Folate PEG Linkers: Transforming Drug Delivery, Diagnostics, and Selective Degradation

What Are Folate PEG Linkers?

Folate PEG linkers combine polyethylene glycol (PEG) with folic acid to target folate receptors commonly found on cancer and inflammation-related cells.

How Do They Work?

Folate receptors naturally bind folic acid, helping transport it into cells. By linking folic acid with PEG, these linkers precisely target these receptors for drug delivery, advanced diagnostics, and selective degradation of harmful cells.

Key Applications:

• Targeted Drug Delivery: Direct therapeutic agents to cancerous and inflammatory cells, improving treatment while minimizing harm to healthy cells.
• Advanced Imaging: Enhance disease tracking and diagnostics, offering critical insights.
• Receptor Quantification: Use folate PEG probes to measure folate receptor density, providing data on cell behavior.
• Selective Degradation: Apply folate receptor chimeras for the targeted degradation of specific cells, improving therapeutic outcomes.
• Enhanced Research: Study cell metabolism, DNA synthesis, and protein production by targeting folate receptors.

AxisPharm: Your Partner in Folate PEG Linkers

AxisPharm leads in folate PEG linkers, offering a range of products for drug delivery, imaging, receptor quantification, and selective degradation. Product Citation: Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo; Nucleic Acids Research, 2024, 52, 4799–4817