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Cyanine dyes feature a polymethine bridged chain structure, offering stable fluorescence, a high molar absorption coefficient, and a high quantum yield. These properties make cyanine dyes ideal for labeling biomolecules like DNA and proteins, providing bright and reliable signals for imaging and molecular detection in various research applications.

AxisPharm provides our clients with a full range of CY dyes, such as CY3, CY3.5, CY5, CY5.5, CY7 , CY7.5, and their Sulfo- analogues.

Cat# Name Structure M.W. Purity Pricing
Cyanine 3 Dye
AP14685Cyanine3 dimethyl484.43≥95% Pricing
AP12708Cyanine3 carboxylic acid493.08≥ (95%) Pricing
AP12705Cyanine3 alkyne530.14≥95% Pricing
AP12710Cyanine3 hydrazide543.57≥ (95%) Pricing
AP14019Cyanine3B carboxylic acid560.67≥95% Pricing
AP12707Cyanine3 azide575.19≥ (95%) Pricing
AP14218N-methyl-N'-(azide-PEG3)-Cy3580.20≥95% Pricing
AP12463Cy3 Acid616.74≥95% Pricing
AP12706Cyanine3 amine627.73≥ (95%) Pricing
AP12712Cyanine3 NHS ester641.5≥ (95+%) Pricing
AP12713Cyanine3 NHS ester minimal dye641.50≥functional for testing Pricing
AP15233Cyanine3B azide642.78≥95 Pricing
AP14016Cy3B NHS Ester657.21≥95% Pricing
AP14074Cyanine3B NHS ester657.75≥95% Pricing
AP12711Cyanine3 maleimide666.56≥ (95%) Pricing
AP12466Cy3 Amine672.86≥95% Pricing
AP15232Cyanine3B maleimide682.79≥95% Pricing
AP14274Cyanine3B amine695.33≥95% Pricing
AP12464Cy3 NHS ester713.82≥95% Pricing
AP12714Cyanine3 tetrazine727.65≥ (95%) Pricing
AP14058Cy3 Tyramide735.91 (protonated)≥95% Pricing
AP12465Cy3 Maleimide738.87≥95% Pricing
AP14055Cy3 Alkyne761.92 (protonated)≥95% Pricing
AP14210N-(m-PEG4)-N'-(azide-PEG4)-Cy3800.40≥95% Pricing
AP14056Cy3 Azide806.96 (protonated)≥95% Pricing
AP14225N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3829.50≥95% Pricing
AP13838Cyanine3 phosphoramidite, 5'-terminal841.81≥95% Pricing
AP14222N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3860.50≥95% Pricing
AP15289Cyanine3B DBCO861.08≥95% Pricing
AP12609Cy3 Tetrazine894.05≥95% Pricing
AP12709Cyanine3 DBCO902.99≥ (95%) Pricing
AP12562Cy3 Methyltetrazine908.07≥95% Pricing
AP14057Cy3 Picolyl Azide927.08 (protonated)≥95% Pricing
AP12672Cy3 Azide Plus945.15 (protonated)≥95% Pricing
AP15331Cyanine 3 Phosphoramidite953.64≥95% Pricing
AP12696Cy3 DBCO983.18≥95% Pricing
AP15238BCN-PEG4-Cyanine3 (exo)1014.79≥95% Pricing
AP14078Cy3 Gly-Gly-Gly1098.31≥95% Pricing
Cyanine3.5 Dye
AP15240Cyanine3.5 dimethyl493.08≥95% Pricing
AP12716Cyanine3.5 carboxylic acid593.20≥ (95%) Pricing
AP12715Cyanine3.5 azide717.38≥ (95%) Pricing
AP12717Cyanine3.5 NHS ester741.62≥ (95%) Pricing
AP12718Cyanine3.5 DBCO944.97≥95% Pricing
Cyanine5 Dye
AP15243Cyanine5 dimethyl510.46≥95% Pricing
AP12722Cyanine5 carboxylic acid519.12≥95% Pricing
AP14220N-methyl-N'-(hydroxy-PEG2)-Cy5537.10≥95% Pricing
AP12719Cyanine5 alkyne556.18≥ (95%) Pricing
AP12724Cyanine5 hydrazide569.61≥ (95%) Pricing
AP12721Cyanine5 azide601.22≥ (95%) Pricing
AP14221N-methyl-N'-(propargyl-PEG4)-Cy5620.30≥95% Pricing
AP15242Cyanine5 Boc-hydrazide633.26≥95% Pricing
AP14215N-(m-PEG4)-N'-hydroxypropyl-Cy5639.30≥95% Pricing
AP12720Cyanine5 amine653.77≥ (95%) Pricing
AP12727Cyanine5 NHS ester minimal dye667.54≥functional for testing Pricing
AP12726Cyanine5 NHS ester667.54≥ (95%) Pricing
AP14219N-methyl-N'-(Azido-PEG2-C5)-Cy5675.30≥95% Pricing
AP12469Cy5 Amine698.89≥95% Pricing
AP14204N-(m-PEG4)-N'-(hydroxy-PEG2)-Cy5713.40≥95% Pricing
AP15630LumiTracker® Mito Red FM724≥95% Pricing
AP14205N-(hydroxy-PEG2)-N'-(azide-PEG3)-Cy5724.30≥95% Pricing
AP14203N-(hydroxy-PEG2)-N'-(propargyl-PEG4)-Cy5737.40≥95% Pricing
AP12467Cy5 NHS ester739.86≥95% Pricing
AP13458N-(m-PEG4)-N'-(PEG2-acid)-Cy5741.4≥97% Pricing
AP12725Cyanine5 maleimide750.77≥ (95%) Pricing
AP14208N-(m-PEG4)-N'-(amino-PEG3)-Cy5 TFA salt756.40≥95% Pricing
AP14065Cy5 Tyramide761.28 (protonated)≥95% Pricing
AP12468Cy5 Maleimide764.91≥95% Pricing
AP13461N-(m-PEG4)-N'-(acid-PEG3)-Benzothiazole Cy5765.4≥98% Pricing
AP13456Cy5-PEG4-acid766.4≥96% Pricing
AP14290N-(azide-PEG4)-3,3-Dimethyl-3H-indole-N'-(m-PEG3)-Benzothiazole Cy5772.40≥95% Pricing
AP13462N-(m-PEG4)-33-Dimethyl-3H-indole-N'-(acid-PEG3)-Benzothiazole Cy5775.4≥98% Pricing
AP13465N,N'-bis-(acid-PEG3)-Benzothiazole Cy5779.4≥98% Pricing
AP14209N-(m-PEG4)-N'-(azide-PEG3)-Cy5782.40≥95% Pricing
AP14059Cy5 Alkyne787.96 (protonated)≥95% Pricing
AP14287N,N'-bis-(azide-PEG3)-Cy5793.40≥95% Pricing
AP12729Cyanine5 tetrazine811.84≥ (95%) Pricing
AP12728Cyanine5 phosphoramidite816.49≥, 31P, (80%) Pricing
AP14286N,N'-bis-(propargyl-PEG4)-Cy5819.50≥95% Pricing
AP13459N-(m-PEG4)-N'-(PEG4-acid)-Cy5829.5≥98% Pricing
AP14060Cy5 Azide834.01 (protonated)≥95% Pricing
AP13399N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5838.4≥97% Pricing
AP13464N-(azide-PEG3)-N'-(PEG4-acid)-Cy5840.5≥96% Pricing
AP13457Cy5-PEG6-acid854.5≥96% Pricing
AP14226N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5855.50≥95% Pricing
AP14212N-(m-PEG4)-N'-(Boc-NH-PEG3)-Cy5856.5≥95% Pricing
AP14223N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5886.50≥95% Pricing
AP14291N-(azide-PEG3)-N'-(Amine-C3-PEG4)-Cy5896.60≥95% Pricing
AP13288N-(m-PEG4)-N'-(PEG3-Mal)-Cy5907.6≥90% Pricing
AP12606Cy5 Tetrazine919.27≥95% Pricing
AP14061Cy5 Azide NHS Ester922.08≥95% Pricing
AP13400N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5926.6≥95% Pricing
AP14207N-(m-PEG4)-N'-(4-hydroxycyclohexyl-1-amido-PEG4)-Cy5926.60≥95% Pricing
AP12723Cyanine5 DBCO929.03≥ (95%) Pricing
AP13463N-methyl-N'-methyl-O-(m-PEG4)-O'-(acid-PEG5)-Cy5 933.6≥98% Pricing
AP12563Cy5 Methyltetrazine934.1≥95% Pricing
AP13401N-(azide-PEG3)-N'-(PEG4-NHS ester)-Cy5937.5≥95% Pricing
AP13402Cy5-PEG6-NHS ester951.6≥96% Pricing
AP14063Cy5 Picolyl Azide953.15 (protonated)≥95% Pricing
AP14230Sulfo-Cy5-TCO959.20≥95% Pricing
AP12578Cy5-TCO959.2≥95% Pricing
AP13287N-(azide-PEG3)-N'-(Mal-PEG4)-Cy5962.6≥90% Pricing
AP12673Cy5 Azide Plus971.18 (protonated)≥95% Pricing
AP13561N-(m-PEG4)-N'-(biotin-PEG3)-Cy5982.7≥98% Pricing
AP14224N-methyl-N'-methyl-O-(m-PEG4)-O'-(PEG5-t-butyl ester)-Cy5989.7≥95% Pricing
AP12695Cy5 DBCO1009.22≥95% Pricing
AP13880N-(m-PEG4)-N'-(DBCO-PEG4)-Cy51087.80≥95% Pricing
AP13460N-(m-PEG9)-N'-(PEG5-acid)-Cy51093.8≥97% Pricing
AP14062Cy5 DBCO NHS Ester1098.30≥95% Pricing
AP12569Cy5 Biotin1137.40≥95% Pricing
AP14214N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy51207.90≥95% Pricing
AP14216N-(m-PEG9)-N'-(propargyl-PEG9)-Cy5 TFA salt1236.00≥95% Pricing
AP14213N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy51239.00≥95% Pricing
AP12612Cy5 Biotin Azide1494.82≥95% Pricing
AP13560N-(m-PEG4)-N'-(Biotin-PEG2-Amido-PEG4)-Cy5 2884.7≥98% Pricing
Cyanine5.5 Dye
AP15297Cyanine5.5 dimethyl610.58≥95% Pricing
AP12733Cyanine5.5 carboxylic acid619.23≥ (95%) Pricing
AP12730Cyanine5.5 alkyne656.30≥ (95%) Pricing
AP12735Cyanine5.5 hydrazide669.73≥ (95%) Pricing
AP12732Cyanine5.5 azide701.34≥ (95%) Pricing
AP12736Cyanine5.5 maleimide741.36≥ (95%) Pricing
AP12731Cyanine5.5 amine753.88≥ (95%) Pricing
AP12737Cyanine5.5 NHS ester767.66≥ (95%) Pricing
AP12739Cyanine5.5 tetrazine911.96≥ (95%) Pricing
AP12738Cyanine5.5 phosphoramidite, 5'-terminal916.61≥, 31P, (85%) Pricing
AP12476Cy5.5 Alkyne954.11≥95% Pricing
AP12472Cy5.5 Amine973.16≥95% Pricing
AP12473Cy5.5 Azide999.15≥95% Pricing
AP12470Cy5.5 NHS ester1014.12≥95% Pricing
AP12734Cyanine5.5 DBCO1029.14≥95% Pricing
AP12471Cy5.5 Maleimide1039.17≥95% Pricing
AP12474Cy5.5 Picolyl Azide1119.26≥95% Pricing
AP12475Cy5.5 DBCO1175.37≥95% Pricing
Cyanine7 Dye
AP12743Cyanine7 carboxylic acid585.22≥ (95%) Pricing
AP12740Cyanine7 alkyne622.28≥ (95%) Pricing
AP12746Cyanine7 hydrazide635.71≥ (95%) Pricing
AP12742Cyanine7 azide667.33≥ (95%) Pricing
AP12745Cyanine7 dicarboxylic acid685.33≥ (95%) Pricing
AP12747Cyanine7 maleimide707.34≥ (95%) Pricing
AP12741Cyanine7 amine719.87≥ (95%) Pricing
AP12748Cyanine7 NHS ester733.64≥ (95%) Pricing
AP12749Cyanine7 tetrazine768.45≥ (95%) Pricing
AP14292N-(Ac-PEG3)-N'-(azide-PEG3)-Cy7792.40≥95% Pricing
AP14211N-(m-PEG4)-N'-(azide-PEG4)-Cy7852.50≥95% Pricing
AP14288N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7894.00≥95% Pricing
AP12744Cyanine7 DBCO995.13≥ (95%) Pricing
AP15274Merocyanine retinal analog (MCRA)267.372≥ (95%) Pricing
AP12570Cy7 Alkyne1010.22≥95% Pricing
AP14066Cy7 Azide1056.27≥95% Pricing
AP12588Cy7 NHS Ester1098.28 (protonated)≥90% Pricing
AP12566Cy7 Methyltetrazine1184.42≥95% Pricing
AP12605Cy7 Picolyl Azide1203.43≥95% Pricing
AP12567Cy7 DBCO1259.53 (protonated)≥95% Pricing
AP14067Cy7 Gly-Gly-Gly 1374.66 (protonated)≥95% Pricing
Cyanine7.5
AP15405Cyanine7.5 dimethyl585.24≥NMR 1H and HPLC-MS (95+%) Pricing
AP12753Cyanine7.5 carboxylic acid685.34≥ (95%) Pricing
AP12750Cyanine7.5 alkyne722.40≥ (95%) Pricing
AP12754Cyanine7.5 hydrazide735.82≥ (95%) Pricing
AP12752Cyanine7.5 azide767.44≥ (95%) Pricing
AP12755Cyanine7.5 maleimide807.46≥ (95%) Pricing
AP12751Cyanine7.5 amine819.99≥ (95%) Pricing
AP12756Cyanine7.5 NHS ester833.76≥ (95%) Pricing
AP12757Cyanine7.5 tetrazine919.9≥ (95%) Pricing
Sulfo Cyanine3 Dye
AP12758sulfo-Cyanine3 antibody labeling kit≥95% Pricing
AP13770Sulfo-Cyanine3 hydrazide630.78≥95% Pricing
AP13139sulfo-Cyanine3 streptavidin≥95% Pricing
AP15573sulfo-Cyanine3 dimethyl554.73≥95% Pricing
AP12762Sulfo-Cyanine3 carboxylic acid654.84≥ (95%) Pricing
AP14235Sulfo-Cyanine3 Alkyne691.90≥95% Pricing
AP12759Sulfo-Cyanine3 alkyne691.90≥ (95%) Pricing
AP12760Sulfo-Cyanine3 amine714.94≥ (95%) Pricing
AP14236diSulfo-Cy3 azide720.80≥95% Pricing
AP14238diSulfo-Cy3 NHS Ester735.80≥95% Pricing
AP12761Sulfo-Cyanine3 azide736.94≥ (95%) Pricing
AP12766Sulfo-Cyanine3 NHS ester751.91≥ (95%) Pricing
AP12481Sulfo Cy3 Alkyne761.92≥95% Pricing
AP13140sulfo-Cyanine3 tyramide774.02≥95% Pricing
AP12765Sulfo-Cyanine3 maleimide777.97≥ (95+%) Pricing
AP12478Sulfo-Cy3 Azide806.96≥95% Pricing
AP12477Sulfo Cy3 NHS ester821.93 (protonated)≥95% Pricing
AP12479Sulfo Cy3 Picolyl Azide832.99≥95% Pricing
AP12767Sulfo-Cyanine3 tetrazine838.05≥ (95%) Pricing
AP14434Sulfo-Cy3-Tetrazine894.10≥95% Pricing
AP14435Sulfo-Cy3-Methyltetrazine908.10≥95% Pricing
AP12763Sulfo-Cyanine3 DBCO955.23≥ (95%) Pricing
AP12480Sulfo-Cy3 DBCO983.18≥95% Pricing
AP13769sulfo-Cyanine3-PEG3-biotin1011.32≥95% Pricing
AP14231Sulfo-Cy3-PEG2-TCO1051.20≥95% Pricing
AP12764Sulfo-Cyanine3 dUTP1256.82≥ (95%), testing in enzymatic reaction Pricing
Sulfo Cyanine5 Dye
AP13198sulfo-Cyanine5 streptavidin≥95% Pricing
AP14968Sulfo-Cyanine5 dimethyl580.77≥95% Pricing
AP15237sulfo-Cyanine5 hydrazide656.83≥95% Pricing
AP12777Sulfo-Cyanine5 carboxylic acid681.88≥ (95%) Pricing
AP12773Sulfo-Cyanine5 alkyne717.94≥ (95+%) Pricing
AP12774Sulfo-Cyanine5 amine740.98≥ (95%) Pricing
AP14008Sulfo-Cy5 Acid750.89≥95% Pricing
AP12775Sulfo-Cyanine5 azide762.98≥ (95%) Pricing
AP12483Sulfo Cy5 Maleimide764.91≥95% Pricing
AP12781Sulfo-Cyanine5 NHS ester778.96≥ (95%) Pricing
AP12487Sulfo Cy5 Alkyne787.96≥95% Pricing
AP13381sulfo-Cyanine5 tyramide800.05≥95% Pricing
AP12780Sulfo-Cyanine5 maleimide804.01≥ (95+%) Pricing
AP14279Sulfo-Bis-(N,N'-carboxylic acid)-Cy5823.80≥95% Pricing
AP12484Sulfo Cy5 Azide833≥95% Pricing
AP12482Sulfo-Cy5 NHS ester847.97≥95% Pricing
AP12782Sulfo-Cyanine5 tetrazine864.09≥ (95%) Pricing
AP14432Sulfo-Cy5-Tetrazine920.10≥95% Pricing
AP14433Sulfo-Cy5-Methyltetrazine934.10≥95% Pricing
AP12485Sulfo Cy5 Picolyl Azide953.11≥95% Pricing
AP12776Sulfo-Cyanine5 bis-NHS ester976.14≥ (95%) Pricing
AP12778Sulfo-Cyanine5 DBCO981.27≥ (95%) Pricing
AP12486Sulfo Cy5 DBCO1009.22≥95% Pricing
AP12783Sulfo-Cyanine5-PEG3-Biotin1037.36≥ (95%) Pricing
AP12779Sulfo-Cyanine5 dUTP1282.86≥ (95%), testing in enzymatic reaction Pricing
Sulfo-Cyanine3.5
AP12770Sulfo-Cyanine3.5 carboxylic acid991.26≥ (95%) Pricing
AP12768Sulfo-Cyanine3.5 alkyne1028.32≥ (95%) Pricing
AP13142sulfo-Cyanine3.5 amine1051.38≥95% Pricing
AP12769Sulfo-Cyanine3.5 azide1073.37≥ (95%) Pricing
AP12771Sulfo-Cyanine3.5 NHS ester1088.33≥ (95%) Pricing
sulfo-Cyanine5.5
AP12784sulfo-Cyanine5.5 antibody labeling kit≥95% Pricing
AP12788Sulfo-Cyanine5.5 carboxylic acid1020.33≥ (95%) Pricing
AP12785Sulfo-Cyanine5.5 alkyne1054.36≥ (95%) Pricing
AP12786Sulfo-Cyanine5.5 amine1079.42≥ (95%) Pricing
AP12787Sulfo-Cyanine5.5 azide1102.43≥ (95%) Pricing
AP12792Sulfo-Cyanine5.5 NHS ester1117.40≥ (95%) Pricing
AP12791Sulfo-Cyanine5.5 maleimide1142.45≥ (95%) Pricing
AP15234sulfo-Cyanine5.5 tetrazine1200.53≥95 Pricing
AP12789Sulfo-Cyanine5.5 DBCO1317.69≥ (95%) Pricing
AP12790Sulfo-Cyanine5.5 dUTP1554.97≥ (95%), testing in enzymatic reaction Pricing
sulfo-Cyanine7
AP12793sulfo-Cyanine7 antibody labeling kit≥95% Pricing
AP12798Sulfo-Cyanine7 carboxylic acid746.97≥ (95%) Pricing
AP12794Sulfo-Cyanine7 alkyne785.05≥ (95%) Pricing
AP12795Sulfo-Cyanine7 amine807.08≥ (95%) Pricing
AP12796Sulfo-Cyanine7 azide829.08≥ (95%) Pricing
AP12801Sulfo-Cyanine7 NHS ester845.06≥ (95%) Pricing
AP12799Sulfo-Cyanine7 dicarboxylic acid847.09≥ (95%) Pricing
AP13396sulfo-Cyanine7 tyramide866.16≥95% Pricing
AP12800Sulfo-Cyanine7 maleimide870.11≥ (95%) Pricing
AP12802Sulfo-Cyanine7 tetrazine930.19≥ (95%) Pricing
AP14237diSulfo-Cy7-bis NHS ester1001.20≥95% Pricing
AP12797Sulfo-Cyanine7 bis-NHS ester1041.23≥ (95%) Pricing
AP13771sulfo-Cyanine7 DBCO1047.37≥95% Pricing
sulfo-Cyanine7.5
AP12803sulfo-Cyanine7.5 antibody labeling kit≥95% Pricing
AP12808Sulfo-Cyanine7.5 dimethyl983.28≥ (95%) Pricing
AP12806Sulfo-Cyanine7.5 carboxylic acid1083.41≥ (95%) Pricing
AP12804Sulfo-Cyanine7.5 alkyne1120.46≥ (95%) Pricing
AP13772sulfo-Cyanine7.5 amine1143.50≥95% Pricing
AP12805Sulfo-Cyanine7.5 azide1165.51≥ (95%) Pricing
AP12810Sulfo-Cyanine7.5 NHS ester1180.47≥ (95%) Pricing
AP12807Sulfo-Cyanine7.5 dicarboxylic acid1183.51≥ (95%) Pricing
AP12809Sulfo-Cyanine7.5 maleimide1205.52≥ (95%) Pricing

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    Cyanine dyes possess several unique features that set them apart from other fluorescent dyes, making them particularly valuable in various scientific applications:
    1. Broad Spectral Range:
      • Unlike many other dyes, cyanine dyes cover a wide spectral range from the visible to the near-infrared (NIR) region. This broad coverage allows for flexible selection of excitation and emission wavelengths, making them ideal for multiplexing and multi-color imaging.
    2. Tunable Fluorescence:
      • Cyanine dyes can be chemically modified to adjust their absorption and emission wavelengths. This tunability is achieved by altering the length and structure of the polymethine chain, providing customizable dye options for specific experimental needs.
    3. High Quantum Yield:
      • Cyanine dyes often exhibit a high quantum yield, leading to bright and intense fluorescence signals. This efficiency in light emission makes them ideal for sensitive detection, even at low concentrations.
    4. Superior Photostability:
      • Compared to many traditional fluorescent dyes, cyanine dyes are more resistant to photobleaching, maintaining their fluorescence intensity during extended exposure. This stability is particularly beneficial for applications involving prolonged imaging or repeated measurements.
    5. Near-Infrared Fluorescence:
      • Cyanine dyes are among the few fluorescent dyes that efficiently emit in the near-infrared region. NIR dyes are especially useful in in vivo imaging due to their deep tissue penetration and low background fluorescence, enhancing signal clarity in biological samples.
    6. Versatile Conjugation:
      • Cyanine dyes can be easily conjugated to a variety of biomolecules, including proteins, nucleic acids, and lipids. This versatility allows them to be used in a broad array of applications, from simple labeling tasks to complex molecular probes.
    7. Low Background Fluorescence:
      • In the NIR range, cyanine dyes exhibit low background fluorescence due to minimal autofluorescence from biological tissues, which improves signal-to-noise ratios and enhances imaging clarity.
    These unique characteristics make cyanine dyes particularly well-suited for advanced applications in fluorescence imaging, molecular biology, diagnostics, and in vivo studies, where other dyes may fall short in performance.