Tetrazine – trans-cyclooctene ligation is among the fastest bioconjugation reactions known to date.
This water soluble sulfo-Cyanine3 derivative contains methyltetrazine moiety for the coupling with trans-cyclooctenes. Methyltetrazines possess optimal stability at physiological pH, while maintaining extremely high reactivity towards cyclooctenes.
The fluorophore is bright, photostable, and is also very well visible with naked eye.
AxisPharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.