Showing 41–57 of 57 results

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Cat# Name Structure M.W. Purity Pricing
Bromoacetamido-PEG-DOTA
AP12027Bromoacetamido-PEG5-DOTA787.7≥95% Pricing
DOTA-(t-Butyl)3-PEG-azide
AP11518DOTA-(t-Butyl)3-PEG5-azide861.09≥95% Pricing
DOTA-NHS ESTER
AP15441DOTAM-NHS ester498.53≥90% Pricing
AP13088DOTA-NHS ESTER501.49≥95% Pricing
AP15430DOTA-mono-NHS tris (t-Bu ester)815.8≥94% Pricing
DOTA-PEG-amine
AP12200DOTA-PEG5-amine HCl salt666.77≥95% Pricing
DOTA-PEG-azide
AP11517DOTA-PEG5-azide692.77≥95% Pricing
AP15427Azido-mono-amide-DOTA-tris(t-Bu ester)735.8≥94% Pricing
AP15411DOTA-PEG4-azide hydrochloride750.51≥NMR 1H and HPLC-MS (95+%) Pricing
DOTA-PEG-DBCO
AP15446DO3A-DBCO776.8≥94% Pricing
AP15445Deferoxamine-DBCO848≥94% Pricing
AP11147DOTA-PEG5-C6-DBCO982.14≥95% Pricing
FA-PEG-DOTA
AP13089FA-PEG3-DOTA1002.05≥95% Pricing
AP13135DOTA-PEG(24)-TFP*2TFA1680.81*228.05≥95% Pricing
Other DOTA PEG
AP15418DOTAGA-tetra (t-Bu ester)700.9≥94% Pricing
AP15437NO2A-Butyne354.4≥94% Pricing
AP15420p-NO₂-Bn-Cyclen307.4≥94% Pricing
AP15422DOTAM-mono-acid401.5≥95% Pricing
AP15444DOTAM-bis-acid438.5≥94% Pricing
AP15459NO2A-Butyne-bis (t-Butyl ester)466.6≥94% Pricing
AP15438NO2A-Azide494.8≥94% Pricing
AP15309DOTA(OtBu)3572.73≥95% Pricing
AP15453p-NH2-Bn-NOTA517.4≥94% Pricing
AP13134DOTA-PNP525.51≥95% Pricing
AP15435Maleimido-mono-amide-NOTA539.5≥94% Pricing
AP15447NODAGA-tris(t-Bu ester)543.7≥94% Pricing
AP15450p-SCN-Bn-NOTA559.9≥94% Pricing
AP15457p-NH2-Bn-oxo-DO3A561.5≥94% Pricing
AP15462Labetuzumab govitecan154K≥95% Pricing
AP15439p-NH₂-Bn-PCTA594.5≥94% Pricing
AP15451p-SCN-Bn-oxo-DO3A603.9≥94% Pricing
AP15436DTPA-tetra (t-Bu ester)617.8≥94% Pricing
AP15458p-SCN-Bn-PCTA637≥94% Pricing
AP15452p-NH₂-Bn-DTPA644.3≥94% Pricing
AP15455p-SCN-Bn-DTPA649.9≥94% Pricing
AP15426p-NH₂-Bn-DOTA655.4≥94% Pricing
AP15434Butyne-DOTA683.6≥94% Pricing
AP15424p-NO2-Bn-DOTA685.4≥94% Pricing
AP15432p-SCN-Bn-DOTA687.8≥94% Pricing
AP15433DO3A-Thiol691.6≥94% Pricing
AP15448p-SCN-Bn-TCMC693.5≥94% Pricing
AP154252-Aminoethyl-mono-amide-DOTA-tris(t-Bu ester)695.7≥94% Pricing
AP15460p-SCN-Bn-CHX-A”-DTPA704≥94% Pricing
AP15449Deferoxamine-maleimide711.8≥94% Pricing
AP15440p-SCN-Bn-Deferoxamine752.9≥94% Pricing
AP154564-Aminobutyl-DOTA766.4≥94% Pricing
AP15423Butyne-DOTA-tris(t-butyl ester)769.8≥94% Pricing
AP15454p-NH2-Bn-DTPA-penta (t-Bu ester)779≥94% Pricing
AP15419Maleimido-mono-amide-DOTA786.5≥94% Pricing
AP15442Fmoc-L-Lys-DOTAM788.3≥94% Pricing
AP154314-Aminobutyl-DOTA-tris (t-butyl ester)788.8≥94% Pricing
AP15429Maleimido-mono-amide-DOTA-tris (t-Bu ester)840.8≥94% Pricing
AP15428p-NH₂-Bn-DOTA-tetra(t-Bu ester)848≥94% Pricing
AP15461Maleimido-mono-amide-DTPA857.5≥94% Pricing
AP15443DOTAM-maleimide865.66≥95% Pricing
AP15463p-SCN-Bn-HEHA for Actinium972.6≥94% Pricing
AP15421Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester)1069.1≥94% Pricing

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    DOTA PEG Linkers: Enhancing Targeted Imaging and Therapy Overview: DOTA PEG linkers are essential tools in pharmaceutical research, combining a DOTA chelator with a polyethylene glycol (PEG) chain. The DOTA moiety binds to metal ions like copper, gallium, or lutetium, while PEG enhances stability and solubility. Applications:
    • Targeted Molecular Imaging and Therapy: Conjugating DOTA PEG linkers to targeting molecules (e.g., antibodies or ligands) enables selective delivery of therapeutic agents. The DOTA chelator can also label the conjugate with radioactive isotopes for non-invasive imaging.
    • Novel Therapeutics: Used in developing treatments for cancer, neurological disorders, and inflammatory diseases, DOTA PEG linkers improve pharmacokinetics by extending drug half-life and reducing immunogenicity.
    Benefits:
    • Increased Stability and Solubility: PEG enhances the properties of the conjugate.
    • Enhanced Targeting: Enables precise delivery and imaging of specific cells or tissues.
    In summary, DOTA PEG linkers play a crucial role in advancing targeted therapies and imaging techniques, offering improved drug delivery and diagnostic capabilities. ref: Parry JJ, Kelly TS, Andrews R, Rogers BE. In vitro and in vivo evaluation of 64Cu-labeled DOTA-linker-bombesin(7-14) analogues containing different amino acid linker moieties. Bioconjug Chem. 2007 Jul-Aug;18(4):1110-7. doi: 10.1021/bc0603788. Epub 2007 May 16. PMID: 17503761.