DOTA-NHS ester CAS:170908-81-3, a small molecule drug, finds application in medical imaging and radiotherapy. It comprises DOTA, NHS, and ester groups. DOTA, a chelator, binds to metal ions, including radioactive ones like gallium-68 or lutetium-177. NHS, a reactive group, links DOTA to targeting molecules (e.g., antibodies or peptides) for targeted drug delivery. The ester group enhances drug solubility and stability. DOTA-NHS ester is commonly employed in positron emission tomography (PET) for visualizing metabolic processes by attaching it to targeting molecules. Furthermore, it is used in radiotherapy to deliver targeted radiation therapy to cancer cells using the radioactive metal ion.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.