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DOTA Reagent DOTA PEG

Cat# Name Structure M.W. Purity Pricing
Bromoacetamido-PEG-DOTA
AP12027Bromoacetamido-PEG5-DOTA
Quick viewBromoacetamido-PEG5-DOTA
787.7≥95% Pricing
DOTA-(t-Butyl)3-PEG-azide
AP11518DOTA-(t-Butyl)3-PEG5-azide
Quick viewDOTA-(t-Butyl)3-PEG5-azide
861.09≥95% Pricing
DOTA-NHS ESTER
AP13088DOTA-NHS ESTER
Quick viewDOTA-NHS ESTER
501.49≥95% Pricing
DOTA-PEG-amine
AP12200DOTA-PEG5-amine HCl salt
Quick viewDOTA-PEG5-amine HCl salt
666.77≥95% Pricing
DOTA-PEG-azide
AP11517DOTA-PEG5-azide
Quick viewDOTA-PEG5-azide
692.77≥95% Pricing
AP15411DOTA-PEG4-azide hydrochloride
Quick viewDOTA-PEG4-azide hydrochloride
750.51≥NMR 1H and HPLC-MS (95+%) Pricing
DOTA-PEG-DBCO
AP11147DOTA-PEG5-C6-DBCO
Quick viewDOTA-PEG5-C6-DBCO
982.14≥95% Pricing
FA-PEG-DOTA
AP13089FA-PEG3-DOTA
Quick viewFA-PEG3-DOTA
1002.05≥95% Pricing
AP13135DOTA-PEG(24)-TFP*2TFA
Quick viewDOTA-PEG(24)-TFP*2TFA
1680.81*228.05≥95% Pricing
Other DOTA PEG
AP15418DOTAGA-tetra (t-Bu ester)
Quick viewDOTAGA-tetra (t-Bu ester)
700.9≥94% Pricing
AP15437NO2A-Butyne
Quick viewNO2A-Butyne
354.4≥94% Pricing
AP15420p-NO₂-Bn-Cyclen
Quick viewp-NO₂-Bn-Cyclen
307.4≥94% Pricing
AP15422DOTAM-mono-acid
Quick viewDOTAM-mono-acid
401.5≥95% Pricing
AP15438NO2A-Azide
Quick viewNO2A-Azide
494.8≥94% Pricing
AP15309DOTA(OtBu)3
Quick viewDOTA(OtBu)3
572.73≥95% Pricing
AP13134DOTA-PNP
Quick viewDOTA-PNP
525.51≥95% Pricing
AP15435Maleimido-mono-amide-NOTA
Quick viewMaleimido-mono-amide-NOTA
539.5≥94% Pricing
AP15439p-NH₂-Bn-PCTA
Quick viewp-NH₂-Bn-PCTA
594.5≥94% Pricing
AP15436DTPA-tetra (t-Bu ester)
Quick viewDTPA-tetra (t-Bu ester)
617.8≥94% Pricing
AP15426p-NH₂-Bn-DOTA
Quick viewp-NH₂-Bn-DOTA
655.4≥94% Pricing
AP15434Butyne-DOTA
Quick viewButyne-DOTA
683.6≥94% Pricing
AP15424p-NO2-Bn-DOTA
Quick viewp-NO2-Bn-DOTA
685.4≥94% Pricing
AP15432p-SCN-Bn-DOTA
Quick viewp-SCN-Bn-DOTA
687.8≥94% Pricing
AP15433DO3A-Thiol
Quick viewDO3A-Thiol
691.6≥94% Pricing
AP154252-Aminoethyl-mono-amide-DOTA-tris(t-Bu ester)
Quick view2-Aminoethyl-mono-amide-DOTA-tris(t-Bu ester)
695.7≥94% Pricing
AP15427Azido-mono-amide-DOTA-tris(t-Bu ester)
Quick viewAzido-mono-amide-DOTA-tris(t-Bu ester)
735.8≥94% Pricing
AP15440p-SCN-Bn-Deferoxamine
Quick viewp-SCN-Bn-Deferoxamine
752.9≥94% Pricing
AP15423Butyne-DOTA-tris(t-butyl ester)
Quick viewButyne-DOTA-tris(t-butyl ester)
769.8≥94% Pricing
AP15419Maleimido-mono-amide-DOTA
Quick viewMaleimido-mono-amide-DOTA
786.5≥94% Pricing
AP154314-Aminobutyl-DOTA-tris (t-butyl ester)
Quick view4-Aminobutyl-DOTA-tris (t-butyl ester)
788.8≥94% Pricing
AP15430DOTA-mono-NHS tris (t-Bu ester)
Quick viewDOTA-mono-NHS tris (t-Bu ester)
815.8≥94% Pricing
AP15429Maleimido-mono-amide-DOTA-tris (t-Bu ester)
Quick viewMaleimido-mono-amide-DOTA-tris (t-Bu ester)
840.8≥94% Pricing
AP15428p-NH₂-Bn-DOTA-tetra(t-Bu ester)
Quick viewp-NH₂-Bn-DOTA-tetra(t-Bu ester)
848≥94% Pricing
AP15421Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester)
Quick viewFmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester)
1069.1≥94% Pricing

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    DOTA PEG Linkers: Enhancing Targeted Imaging and Therapy Overview: DOTA PEG linkers are essential tools in pharmaceutical research, combining a DOTA chelator with a polyethylene glycol (PEG) chain. The DOTA moiety binds to metal ions like copper, gallium, or lutetium, while PEG enhances stability and solubility. Applications:
    • Targeted Molecular Imaging and Therapy: Conjugating DOTA PEG linkers to targeting molecules (e.g., antibodies or ligands) enables selective delivery of therapeutic agents. The DOTA chelator can also label the conjugate with radioactive isotopes for non-invasive imaging.
    • Novel Therapeutics: Used in developing treatments for cancer, neurological disorders, and inflammatory diseases, DOTA PEG linkers improve pharmacokinetics by extending drug half-life and reducing immunogenicity.
    Benefits:
    • Increased Stability and Solubility: PEG enhances the properties of the conjugate.
    • Enhanced Targeting: Enables precise delivery and imaging of specific cells or tissues.
    In summary, DOTA PEG linkers play a crucial role in advancing targeted therapies and imaging techniques, offering improved drug delivery and diagnostic capabilities. ref: Parry JJ, Kelly TS, Andrews R, Rogers BE. In vitro and in vivo evaluation of 64Cu-labeled DOTA-linker-bombesin(7-14) analogues containing different amino acid linker moieties. Bioconjug Chem. 2007 Jul-Aug;18(4):1110-7. doi: 10.1021/bc0603788. Epub 2007 May 16. PMID: 17503761.