Biotin-PEG-Biotin is a polymer that consists of two biotin molecules connected by a polyethylene glycol (PEG) linker. Biotin, also known as vitamin H, is a water-soluble B-complex vitamin that plays an important role in various biological processes. PEG, on the other hand, is a biocompatible and hydrophilic polymer that has been extensively used in drug delivery and biomedical applications.
The functional groups in Biotin-PEG-Biotin are the biotin moieties and the PEG linker. Biotin is known to have a high affinity for avidin or streptavidin proteins, which can be used as molecular tags for the detection and purification of biomolecules. The PEG linker provides flexibility and stability to the molecule, as well as a hydrophilic surface that prevents nonspecific interactions with biological molecules.
In pharmaceutical research and development, Biotin-PEG-Biotin has been used as a versatile tool for the conjugation of biotinylated molecules to various surfaces or carriers. For example, it can be used to immobilize proteins, peptides, or antibodies onto solid supports for diagnostic or therapeutic purposes. It can also be used to functionalize nanoparticles or liposomes for targeted drug delivery or imaging.