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Diazirine linkers, such as trifluoromethyl phenyl DAs and alkyl DAs, generate reactive carbene species via loss of N2 upon photoirradiation at 350 nm. This active carbene easily inserts into neighboring C–H or heteroatom–H bonds and forms a covalent adduct. Additionally, the generated carbene has a quick half-life in the nanosecond range.

Diazirine Linkers
Cat# Name Structure M.W. Purity Pricing
AP110162-(3-Methyl-3H-diazirin-3-yl)ethan-1-amine99.13≥95% Pricing
AP110172-(3-Methyl-3H-diazirin-3-yl)ethanol100.12≥95% Pricing
AP110183-methyl-3H-diazirin-3-propanol114.15≥95% Pricing
AP110103-(3-Methyl-3H-diazirin-3-yl)propanoic acid128.13≥95% Pricing
AP110152-(3-But-3-ynyl-3H-Diazirin-3-yl)-ethanol138.17≥95% Pricing
AP110113-[3-(but-3-yn-1-yl)-3H-diazirin-3-yl]propanoic acid166.18≥95% Pricing
AP11020(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)phenyl)methanamine215.18≥95% Pricing
AP11019{4-[3-(trifluoromethyl)-3H-diazirin-3-yl]phenyl}methanol216.16≥95% Pricing
AP110124-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzoic acid230.14≥95% Pricing
AP110144-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzyl Bromide279.06≥95% Pricing
AP11013Benzoic acid, 4-[3-(trifluoromethyl)-3H-diazirin-3-yl] NHS327.22≥95% Pricing
AP11059Diazo Biotin-PEG3-alkyne795.95≥95% Pricing

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