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Val-cit-pab linkers have been widely used in Antibody drug conjugation development. They have superior plasma stability to other peptide linkers. Val-cit-pab linkers are cleavable by cathepsin. The cleavage of val-cit-PAB linked amide releases the free parent drug through a 1,6-elimination of carbon dioxide.

Mc-val-cit-pab linker is a peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs) for various ADC payloads.

Catalog# Name Structure M.W. Purity Pricing
Val-Cit-PAB Linkers
AP10895BCN-PEG1-Val-Cit-OH565.67≥95% Pricing
AP10896BCN-PEG1-Val-Cit-PABC-OH670.81≥95% Pricing
AP10897BCN-PEG1-Val-Cit-PABC-PNP835.91≥95% Pricing
AP11194Azido-PEG3-Val-Cit-PAB-OH608.7≥95% Pricing
AP11196Azido-PEG3-Val-Cit-PAB-PNP773.8≥95% Pricing
AP11195Azido-PEG4-Val-Cit-PAB-OH652.75≥95% Pricing
AP11197BCN-PEG3-Val-Cit653.77≥95% Pricing
AP11198BCN-PEG3-VC-PFP Ester819.82≥95% Pricing
AP11192Mal-amido-PEG2-Val-Cit-PAB-OH689.77≥95% Pricing
AP11193Mal-amido-PEG2-Val-Cit-PAB-PNP854.87≥95% Pricing
AP11191Mal-PEG4-Val-Cit-PAB-PNP871.9≥95% Pricing
AP11921MC (C5)-Val-Cit452.51≥95% Pricing
AP11922SPDP-Val-Cit-PAB-OH576.73≥95% Pricing
AP11923SPDP-Val-Cit-PAB-PNP741.84≥95% Pricing
AP10899DBCO-PEG1-Val-Cit-PABC-OH694.83≥95% Pricing
AP10891Azido-PEG1-Val-Cit-PABC-PNP685.7≥95% Pricing
AP10892TCO-PEG1-Val-Cit-OH541.65≥95% Pricing
AP10877Mc-Val-Ala-PAB-PNP651.67≥95% Pricing
AP10894TCO-PEG1-Val-Cit-PABC-PNP811.89≥95% Pricing
AP10005Boc-Val-Cit374.4≥95% Pricing
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