Acid-PEG5-TEMPO probe contains a terminal carboxylic acid and a TEMPO moiety. The terminal carboxylic acid readily reacts with primary and secondary amines in the presence of amide coupling reagents, such as EDC, HATU and DCC, etc. TEMPO is a stablefree radical due to its steric hindrance. It is widely used as a radical marker, a structural probe for biological systems in conjunction with electron spin resonance spectroscopy. In organic synthesis and polymer science, it is used as a mediator in controlled radical polymerization and as an oxidation catalyst to convert primary alcohols to aldehydes and secondary alcohols to ketones.
Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.