Acid-PEG14-t-butyl ester is characterized by the presence of an acid functional group at one end and a t-butyl ester group at the other end. The acid group allows for the targeted conjugation of the PEG moiety to primary amine-containing biomolecules, such as peptides, proteins, and antibodies, through amide bond formation. The t-butyl ester group, on the other hand, acts as a protecting group that can be selectively removed under mild acidic conditions, yielding a free carboxylic acid for further derivatization or conjugation if required.
Acid-PEG14-t-butyl ester is a valuable reagent for pharmaceutical research and development, offering unique functional groups that enable the targeted PEGylation of biomolecules and the generation of advanced drug delivery systems, prodrugs, and bioconjugates.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.