Acid-PEG3-PFP ester linker contains a carboxylic acid and a PFP ester end group. After the first PFP ester coupling with an amine-tagged biomolecule, the inherited carboxylic acid group of the resulting substance can then react with amines under amdie coupling conidtions such as EDC, DCC and HATU, etc. The PEG spacer increase the solubility of the compound in aqueous media.
Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.