PLGA Acid Capped (PLGA-COOH, 50:50), MW 160K is a high-molecular-weight poly(lactic-co-glycolic acid) with a terminal carboxylic acid group where its 50:50 lactide composition especially supports biodegradable drug delivery and biomaterial applications.
Key Features and Benefits
- Acid Capped: Provides a terminal carboxyl group for conjugation or surface functionalization.
- 50:50 PLGA Ratio: Offers balanced lactide and glycolide composition for controlled biodegradation.
- High Molecular Weight: ~160 kDa polymer supports durable matrices and sustained-release formulations.
- Biodegradable Polymer: Degrades into lactic acid and glycolic acid under physiological conditions.
- Versatile Material: Suitable for nanoparticles, microspheres, implants, and polymer conjugates.
Applications
- Drug Delivery: Used in sustained and controlled-release formulations.
- Nanoparticles: Supports preparation of biodegradable drug-loaded nanoparticles.
- Microspheres: Suitable for encapsulation and prolonged release of active compounds.
- Bioconjugation: Terminal carboxyl group enables coupling with amine-containing molecules.
- Biomaterials: Used in scaffolds, implants, coatings, and tissue engineering research.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to specifically minimize premature polymer degradation.
PLGA Acid Capped (PLGA-COOH, 50:50), MW 160K combines high molecular weight, biodegradability, and terminal carboxyl functionality, making it an especially versatile polymer for controlled drug delivery and biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.