PLGA Acid Capped (PLGA-COOH, 50:50), MW 2K is a low-molecular-weight biodegradable copolymer with terminal carboxylic acid functionality where its 50:50 lactide ratio specifically supports drug delivery, polymer conjugation, particle formulation, and biomaterial research.
Key Features and Benefits
- Acid Capped: Provides terminal carboxyl functionality for conjugation and further modification.
- 50:50 PLGA Ratio: Offers balanced lactide and glycolide composition for biodegradable formulations.
- MW 2K: Low molecular weight supports efficient processing and relatively rapid polymer degradation.
- Biodegradable: Degrades into lactic acid and glycolic acid under physiological conditions.
- Versatile Polymer: Suitable for polymer conjugates, nanoparticles, coatings, and biodegradable matrices.
Applications
- Drug Delivery: Supports biodegradable drug delivery and controlled-release formulations.
- Bioconjugation: Carboxyl functionality specifically enables coupling with amine-containing molecules.
- Polymer Conjugation: Serves as a functional PLGA building block for further derivatization.
- Nanoparticles: Supports preparation and surface modification of polymeric nanoparticles.
- Biomaterials: Suitable for biodegradable matrices, coatings, and material research.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to minimize premature hydrolysis and polymer degradation.
PLGA Acid Capped (PLGA-COOH, 50:50), MW 2K combines low molecular weight, biodegradability, and terminal carboxyl functionality specifically for drug delivery, polymer conjugation, and biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.