PLGA Acid Capped (PLGA-COOH, 50:50), MW 80K is a biodegradable copolymer with terminal carboxylic acid functionality where its 50:50 lactide ratio and ~80 kDa molecular weight especially support sustained drug delivery, particle formulation, and biomaterial applications.
Key Features and Benefits
- Acid Capped: Provides terminal carboxyl functionality for conjugation and surface modification.
- 50:50 PLGA Ratio: Offers balanced lactide and glycolide composition for controlled biodegradation.
- MW 80K: Intermediate molecular weight supports durable matrices and sustained-release formulations.
- Biodegradable: Degrades into lactic acid and glycolic acid under physiological conditions.
- Versatile Polymer: Suitable for nanoparticles, microspheres, implants, and polymer conjugates.
Applications
- Drug Delivery: Supports sustained and controlled-release formulations.
- Nanoparticles: Used to prepare biodegradable drug-loaded nanoparticles.
- Microspheres: Enables encapsulation and prolonged release of active compounds.
- Bioconjugation: Carboxyl functionality specifically allows coupling with amine-containing molecules.
- Biomaterials: Suitable for scaffolds, coatings, implants, and tissue engineering research.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to minimize premature hydrolysis and polymer degradation.
PLGA Acid Capped (PLGA-COOH, 50:50), MW 80K combines biodegradability, intermediate molecular weight, and terminal carboxyl functionality specifically for sustained drug delivery, particle formulation, and advanced biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.