PLGA Acid Capped (PLGA-COOH, 50:50), MW 15K is a biodegradable copolymer with terminal carboxylic acid functionality where its 50:50 lactide ratio and ~15 kDa molecular weight specifically support controlled drug delivery, particle formulation, and biomaterial applications.
Key Features and Benefits
- Acid Capped: Provides terminal carboxyl functionality for conjugation and surface modification.
- 50:50 PLGA Ratio: Offers balanced lactide and glycolide composition for controlled biodegradation.
- MW 15K: Lower molecular weight supports efficient processing and controlled-release formulations.
- Biodegradable: Degrades into lactic acid and glycolic acid under physiological conditions.
- Versatile Polymer: Suitable for nanoparticles, microspheres, polymer conjugates, and biodegradable matrices.
Applications
- Drug Delivery: Supports controlled and sustained-release formulations.
- Nanoparticles: Used to prepare biodegradable drug-loaded nanoparticles.
- Microspheres: Enables encapsulation and controlled release of active compounds.
- Bioconjugation: Carboxyl functionality specifically enables coupling with amine-containing molecules.
- Biomaterials: Suitable for biodegradable matrices, coatings, scaffolds, and related research.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to minimize premature hydrolysis and polymer degradation.
PLGA Acid Capped (PLGA-COOH, 50:50), MW 15K combines biodegradability, lower molecular weight, and terminal carboxyl functionality for especially controlled drug delivery, particle formulation, and biomaterial development
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.