PLGA Acid Capped (PLGA-COOH, 50:50), MW 5K is a low-molecular-weight biodegradable copolymer with terminal carboxylic acid functionality where its 50:50 lactide ratio specifically supports particle formulation, controlled drug delivery, bioconjugation, and biomaterial research.
Key Features and Benefits
- Acid Capped: Provides terminal carboxyl functionality for conjugation and surface modification.
- 50:50 PLGA Ratio: Offers balanced lactide and glycolide composition for controlled biodegradation.
- MW 5K: Low molecular weight supports efficient processing and relatively rapid polymer degradation.
- Biodegradable: Degrades into lactic acid and glycolic acid under physiological conditions.
- Versatile Polymer: Suitable for nanoparticles, polymer conjugates, coatings, and biodegradable matrices.
Applications
- Drug Delivery: Supports biodegradable controlled-release formulations.
- Nanoparticles: Used to prepare drug-loaded and functionalized polymeric nanoparticles.
- Bioconjugation: Carboxyl functionality specifically enables coupling with amine-containing molecules.
- Polymer Modification: Serves as a functional PLGA building block for further derivatization.
- Biomaterials: Suitable for biodegradable matrices, coatings, and material research.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to minimize premature hydrolysis and polymer degradation.
PLGA Acid Capped (PLGA-COOH, 50:50), MW 5K combines low molecular weight, biodegradability, and terminal carboxyl functionality specifically for drug delivery, polymer modification, and biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.