DSPA (1,2-Distearoyl-sn-glycero-3-phosphate) is an anionic phospholipid containing two saturated C18 stearoyl chains and a phosphate headgroup, while its amphiphilic structure supports lipid membrane formation, liposome research, lipid nanoparticles, and biomaterial development.
Key Features and Benefits
- Phospholipid Structure: DSPA combines two hydrophobic stearoyl chains with a hydrophilic phosphate headgroup.
- C18 Lipid Chains: Two saturated C18 stearoyl chains provide a long-chain hydrophobic lipid component.
- Anionic Phosphate Headgroup: The phosphate group provides an anionic lipid headgroup under appropriate conditions.
- Amphiphilic Character: DSPA contains both hydrophobic and hydrophilic regions, specifically supporting organization in lipid-based systems.
- Lipid Membrane Formation: The phospholipid structure specifically supports incorporation into compatible lipid bilayers and membrane assemblies.
- Lipid Formulation Component: DSPA can serve as an anionic phospholipid component in experimental lipid formulations.
- Surface Charge Modification: The phosphate headgroup specifically supports research involving negatively charged lipid interfaces.
- Versatile Lipid Platform: DSPA supports membrane, nanoparticle, formulation, and biomaterial research.
Applications
- Liposome Research: DSPA supports preparation and investigation of anionic phospholipid-containing liposomes.
- Lipid Nanoparticle Research: Provides an anionic phospholipid component for compatible lipid nanoparticle formulations.
- Lipid Bilayer Research: Supports studies involving phospholipid organization, membrane properties, and lipid interactions.
- Membrane Research: Useful for investigating anionic lipid membranes and related model systems.
- Nanoparticle Formulation: Supports development of lipid-containing nanoparticles and other nanoscale assemblies.
- Surface Charge Research: Enables investigation of negatively charged lipid interfaces and their interactions.
- Drug Delivery Research: Supports development and characterization of experimental lipid-based delivery systems.
- Biomaterial Research: Provides a saturated phospholipid platform for lipid-based biomaterials and formulations.
Storage and Handling
- Storage: Store according to the product specification in a tightly sealed container under dry conditions.
- Handling: Protect from moisture and excessive heat. Allow the material to reach room temperature before opening to minimize condensation.
DSPA (1,2-Distearoyl-sn-glycero-3-phosphate) combines two saturated C18 lipid chains with an anionic phosphate headgroup and specifically provides a versatile phospholipid platform for liposomes, lipid nanoparticles, membrane studies, and biomaterial research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
