DOPA (1,2-Dioleoyl-sn-glycero-3-phosphate) is an anionic phospholipid containing two unsaturated C18:1 oleoyl chains and a phosphate headgroup, while its amphiphilic structure supports lipid membrane formation, liposome research, lipid nanoparticles, and biomaterial development.
Key Features and Benefits
- Phospholipid Structure: DOPA combines two hydrophobic oleoyl chains with a hydrophilic phosphate headgroup.
- C18:1 Oleoyl Chains: Two unsaturated C18:1 chains specifically provide a fluid hydrophobic lipid component.
- Anionic Phosphate Headgroup: The phosphate group specifically provides an anionic lipid headgroup under appropriate conditions.
- Amphiphilic Character: DOPA contains hydrophobic and hydrophilic regions that specifically support organization in lipid-based systems.
- Unsaturated Lipid Structure: Cis double bonds in the oleoyl chains influence membrane packing and lipid bilayer fluidity.
- Lipid Membrane Formation: DOPA supports incorporation into compatible lipid bilayers, liposomes, and membrane assemblies.
- Surface Charge Modification: The phosphate headgroup supports research involving negatively charged lipid interfaces.
- Versatile Lipid Platform: DOPA specifically supports membrane, nanoparticle, formulation, and biomaterial research.
Applications
- Liposome Research: DOPA supports preparation and investigation of anionic phospholipid-containing liposomes.
- Lipid Nanoparticle Research: Provides an anionic phospholipid component for compatible lipid nanoparticle formulations.
- Lipid Bilayer Research: Supports studies of phospholipid organization, membrane properties, and lipid interactions.
- Membrane Research: Useful for investigating anionic and unsaturated lipid membrane systems.
- Nanoparticle Formulation: Supports development of lipid-containing nanoparticles and related nanoscale assemblies.
- Surface Charge Research: Enables investigation of negatively charged lipid interfaces and their interactions.
- Drug Delivery Research: Supports development and characterization of experimental lipid-based delivery systems.
- Biomaterial Research: Provides an unsaturated phospholipid platform for lipid-based materials and formulations.
Storage and Handling
Storage: Store according to the product specification in a tightly sealed container under dry conditions.
Handling: Protect from moisture, excessive heat, and prolonged exposure to air. Allow the material to reach room temperature before opening to minimize condensation.
DOPA (1,2-Dioleoyl-sn-glycero-3-phosphate) combines two unsaturated C18:1 oleoyl chains with an anionic phosphate headgroup. It provides a versatile lipid platform for liposomes, lipid nanoparticles, membrane studies, and biomaterial research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
