Folate-PEG-Azide is used in drug research and development. It has a PEG spacer that improves solubility and stability. The azide group enables efficient bioconjugation. The folate moiety targets folate receptors, often found in cancer cells. It is ideal for cancer therapy and diagnostics.
Folate-PEG-Azide
| Cat# | Name | Structure | Pricing |
|---|---|---|---|
| AP10012 | Folate-PEG2-Azide | Pricing | |
| AP10561 | Folate-PEG3-Azide | Pricing | |
| AP10559 | Folate-PEG4-Azide | Pricing | |
| AP15564 | Folate-PEG7-Azide | Pricing | |
| AP15565 | Folate-PEG11-Azide | Pricing |
Folate-PEG-Azide (Folic Acid-PEG-Azide): Advanced Compound for Drug Research and Development
Overview
Folate-PEG-Azide, also known as Folic Acid-PEG-Azide, is a cutting-edge compound utilized in drug research and development. This innovative folate conjugate features a polyethylene glycol (PEG) spacer and an azide functional group, enhancing its utility in various biomedical applications.
Key Features
- PEG Spacer: The polyethylene glycol (PEG) component improves the solubility, stability, and pharmacokinetics of the compound, making it highly effective for drug delivery systems.
- Azide Functional Group: The azide group is highly reactive, ideal for bioconjugation reactions, which allows Folate-PEG-Azide to be linked with other molecules for advanced applications.
Applications
- Targeted Drug Delivery: The folate component of Folate-PEG-Azide binds specifically to folate receptors, which are often overexpressed in cancer cells. This specificity enables the targeted delivery of cytotoxic drugs or imaging agents directly to cancer cells, enhancing treatment efficacy and reducing off-target effects.
- Bioconjugation: The azide group facilitates efficient bioconjugation, allowing for the attachment of Folate-PEG-Azide to a variety of biomolecules, including proteins, peptides, and other therapeutic agents.
Benefits
- Enhanced Solubility and Stability: The PEG spacer ensures better solubility and stability in biological environments, improving the performance of drug delivery systems.
- Selective Targeting: The folate moiety provides selective binding to folate receptors, which is beneficial for targeted cancer therapies and diagnostic applications.
- Versatile Bioconjugation: The azide functional group enables straightforward bioconjugation, expanding the range of possible applications and enhancing research flexibility.
Applications in Cancer Therapy
Folate-PEG-Azide is particularly promising for cancer therapy due to its ability to target folate receptors, which are commonly overexpressed in various cancer types. By conjugating this compound with therapeutic or imaging agents, researchers can develop more effective treatments and diagnostic tools that minimize side effects and improve patient outcomes.
Conclusion
Folate-PEG-Azide is a valuable tool in drug research and development, offering advanced capabilities for targeted drug delivery and bioconjugation. Its combination of PEG and azide functional groups provides improved solubility, stability, and specificity, making it an essential component for innovative biomedical applications.