Bromoacetamido-PEG-DOTA is a chemical compound that belongs to the family of polyethylene glycol (PEG) derivatives. It contains three distinct functional groups: a bromoacetamide, a PEG linker, and a 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) chelator. This unique combination of functional groups makes Bromoacetamido-PEG-DOTA a valuable tool in drug research and development.
The bromoacetamide group in Bromoacetamido-PEG-DOTA can be used to attach the compound to various biomolecules, such as proteins or peptides, through covalent bonding. This property allows for the targeted delivery of drugs to specific cells or tissues, enhancing their therapeutic efficacy while minimizing off-target effects.
The PEG linker in Bromoacetamido-PEG-DOTA plays a crucial role in improving the pharmacokinetics of the attached drug. It can increase the solubility, stability, and bioavailability of the drug by reducing its clearance rate and preventing its degradation.
Finally, the DOTA chelator in Bromoacetamido-PEG-DOTA can bind to metal ions such as gadolinium or copper, enabling the compound to be used in medical imaging or radiotherapy applications.
Bromoacetamido-PEG-DOTA is a versatile and promising compound in drug research and development due to its unique combination of functional groups and diverse applications in targeted drug delivery, imaging, and radiotherapy.
Bromoacetamido-PEG-DOTA
| Cat# | Name | Structure | Pricing |
|---|---|---|---|
| AP12027 | Bromoacetamido-PEG5-DOTA | Pricing |
