PLGA-di-amine, MW 20K

PLGA-di-amine, MW 20K is a high-molecular-weight linear biodegradable polyester modified with primary amine groups at both molecular terminals. Copolymerized from D,L-lactide and glycolide monomers, this product supports multiple standard lactide-glycolide ratios including 50:50, 65:35, 75:25, 85:15, as well as fully customized ratios to meet advanced material development needs. Benefiting from its extended molecular chain structure, the 20K PLGA-di-amine delivers significantly enhanced structural stability and slower biodegradation kinetics compared with low and medium molecular weight analogs. While maintaining reliable nucleophilic reactivity of dual-terminal amino groups, it enables high-efficiency covalent conjugation with carboxyl and NHS-functionalized substances, facilitating the fabrication of high-stability block copolymers, compact crosslinked hydrogel networks, and long-circulating biodegradable nanoparticles. Its degradation metabolites are fully biocompatible and naturally metabolized in vivo, granting outstanding biological safety. This polymer is highly suitable for designing long-term sustained-release drug delivery systems, durable tissue engineering scaffolds, and high-stability functional biomaterials requiring prolonged in-service cycles.