PLGA-di-amine, MW 10K is a biodegradable PLGA polymer featuring terminal amine functionality and an approximate molecular weight of 10 kDa where its reactive amine groups specifically support bioconjugation, drug delivery, nanoparticle functionalization, and biomaterial applications.
Key Features and Benefits
- Amine Functionalization: Provides reactive amino groups for conjugation and derivatization.
- MW 10K: Low molecular weight supports efficient processing and versatile formulation development.
- Biodegradable: PLGA degrades into lactic acid and glycolic acid under physiological conditions.
- Versatile Conjugation: Amine groups react with NHS esters, activated carboxyl groups, and other amine-reactive reagents.
- Functional Polymer: Suitable for preparing polymer conjugates, functionalized particles, and biodegradable materials.
Applications
- Bioconjugation: Enables attachment of peptides, proteins, ligands, dyes, and other functional molecules.
- Drug Delivery: Supports biodegradable drug delivery and controlled-release systems.
- Nanoparticles: Used to prepare functionalized polymeric nanoparticles and drug carriers.
- Surface Modification: Provides reactive amines for further modification of PLGA-based materials.
- Biomaterials: Suitable for biodegradable matrices, coatings, scaffolds, and related research.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to minimize premature hydrolysis and polymer degradation.
PLGA-di-amine, MW 10K combines biodegradable PLGA with reactive amine functionality, providing an especially versatile polymer platform for bioconjugation, drug delivery, nanoparticle functionalization, and biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.