BCN-PEG6-Maleimide is a linker used in bioconjugation. It has two functional groups: a BCN group for copper-free click chemistry with azides and a maleimide group for binding to thiol groups.
Key Features
- BCN Group:
- Reacts efficiently with azides without copper, protecting sensitive biomolecules.
- Maleimide Group:
- Selectively binds to thiol groups (e.g., cysteine), forming stable bonds.
- PEG6 Spacer:
- Improves solubility and reduces steric hindrance for smoother reactions.
Applications
- Bioconjugation: Attaches biomolecules like proteins and antibodies.
- Drug Delivery: Improves solubility and targeting in drug conjugates.
- Diagnostics: Helps create stable imaging agents and biosensors.
Handling and Storage
- Solubility: Offered as a DMSO solution, dissolves in DMSO, DMF, and similar solvents.
- Storage: Keep at -80°C for stability.
- Precautions: Use protective gear and handle in a ventilated area.
BCN-PEG6-Maleimide is simple and effective for biomedical and research applications, offering reliable bioconjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
