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Copper free click chemistry linkers have been widely used for in vivo bioconjugation applications. Conventional “Click Chemistry” requires the presence of cytotoxic of Cu(I) catalyst, which limits its applications in biological systems. The Copper-free Click Chemistry is based on the reaction of a cyclooctyne (DBCO and BCN) moiety with an azide-labeled reaction partner, known as strain-promoted alkyne azide cycloaddition (SPAAC).

Copper Free Click Chemistry Linkers
  • BCN Linkers
  • DBCO Linkers
  • TCO Linkers
  • Tetrazine Linkers
Catalog# Name Structure M.W. Purity Pricing
Aminooxy-PEG-TCO
AP10105TCO-PEG2-oxyamine316.39≥95% Pricing
AP10104TCO-PEG3-oxyamine360.45≥95% Pricing
AP10107TCO-PEG2-oxyamineBoc416.51≥95% Pricing
AP10106TCO-PEG3-oxyamineBoc460.56≥95% Pricing
AP10141aminooxy-PEG2-TCO HCl Salt in solution373.45≥95% Pricing
AP10142Bocaminooxy-PEG2-TCO473.57≥95% Pricing
BCN Linkers
AP10616Bis-BCN-PEG1-diamide484.64≥95% Pricing
AP10617Bis-BCN-PEG3-diamide572.74≥95% Pricing
AP10739BCN-endo-PEG3-Maleimide519.6≥95% Pricing
AP11022Folate-amido-C2-amine-BCN (endo)659.69≥95% Pricing
AP10738BCN-exo-PEG7-Maleimide739.86≥95% Pricing
AP12344endo-BCN-PEG2-acid353.42≥95% Pricing
AP12345endo-BCN-PEG3-acid397.47≥95% Pricing
AP10736BCN-PEG4-acid441.52≥95% Pricing
AP12346endo-BCN-PEG4-acid441.52≥95% Pricing
AP10790endo-BCN-PEG4 acid441.52≥95% Pricing
AP12347endo-BCN-PEG8-acid617.73≥95% Pricing
AP12348endo-BCN-PEG12-acid793.95≥95% Pricing
AP11023endo-BCN-PEG1-NHS422.43≥95% Pricing
AP12349endo-BCN-PEG2-NHS ester450.49≥95% Pricing
AP12350endo-BCN-PEG3-NHS ester494.54≥95% Pricing
AP10584Endo-BCN-PEG4-NHS ester538.59≥95% Pricing
AP12351endo-BCN-PEG8-NHS ester714.81≥95% Pricing
AP12352endo-BCN-PEG12-NHS ester891.02≥95% Pricing
AP12353endo-BCN-PEG2-PFP ester519.47≥95% Pricing

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