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Copper free click chemistry linkers have been widely used for in vivo bioconjugation applications. Conventional “Click Chemistry” requires the presence of cytotoxic of Cu(I) catalyst, which limits its applications in biological systems. The Copper-free Click Chemistry is based on the reaction of a cyclooctyne (DBCO and BCN) moiety with an azide-labeled reaction partner, known as strain-promoted alkyne azide cycloaddition (SPAAC).

Copper Free Click Chemistry Linkers

PEG Applications

pegylation
ADC-Conjugation
Click-Chemistry
Dye-Labeling
Drug-Delivery

Top 10 selling High purity Copper Free Click Chemistry Linkers

Cat# Name Structure M.W. Purity Pricing
AP10737endo-BCN-PEG4-t-butyl ester497.62≥95% Pricing
AP10322DBCO-NH-PEG4-Biotin749.92≥95% Pricing
AP10855DBCO-Sulfo-Maleimide578.60≥95% Pricing
AP11145Methyltetrazine-PEG12-DBCO1003.16≥95% Pricing
AP10025DBCO-acid305.33≥98% Pricing
AP10030DBCO-PEG3-CH2CO-NHS ester591.61≥98% Pricing
AP11143DBCO-PEG4-triethoxysilane755.98≥95% Pricing
AP10808TCO-PEG1-acid285.34≥95% Pricing
AP10825TCO-PEG4-maleimide468.54≥95% Pricing
AP10856DBCO-Sulfo-PEG4-Maleimide825.89≥95% Pricing

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