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Copper free click chemistry linkers have been widely used for in vivo bioconjugation applications. Conventional “Click Chemistry” requires the presence of cytotoxic of Cu(I) catalyst, which limits its applications in biological systems. The Copper-free Click Chemistry is based on the reaction of a cyclooctyne (DBCO and BCN) moiety with an azide-labeled reaction partner, known as strain-promoted alkyne azide cycloaddition (SPAAC).

Copper Free Click Chemistry Linkers
  • BCN Linkers
  • DBCO Linkers
  • TCO Linkers
  • Tetrazine Linkers
Cat# Name Structure M.W. Purity Pricing
Top selling High purity Copper Free Click Chemistry Linkers
AP10862DBCO-C6-NHS ester430.45≥95% Pricing
AP10030DBCO-PEG3-CH2CO-NHS ester591.61≥98% Pricing
AP10302DBCO-CONH-S-S-COONHS Ester565.66≥95% Pricing
AP11114DBCO-PEG5-NHS ester693.75≥95% Pricing
AP10040TCO PEG3 CH2CONHS456.49≥98% Pricing
AP10317DBCO-NH-PEG2-NHS ester561.58≥95% Pricing
AP10138Mal-NH-PEG2-BCN475.54≥95% Pricing
AP10863DBCO-NHS ester402.40≥95% Pricing
AP10320DBCO-NH-PEG13-NHS ester1046.16≥95% Pricing
AP11116DBCO-PEG12-NHS ester1002.12≥95% Pricing

PEG Applications

ADC Conjugation
Click Chemistry
Dye Labeling
Drug Delivery

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