N3-PEG-OH(Azide-PEG-Hydroxy) contains three distinct functional groups: azide, PEG (polyethylene glycol), and hydroxyl. These functional groups are crucial in designing drug delivery systems, biomaterials, and bioconjugation reactions.
The azide group is widely used in bioconjugation chemistry as a reactive handle for labeling, tagging, or crosslinking biomolecules. PEG is a water-soluble polymer that can improve the solubility, stability, and bioavailability of drugs. Additionally, PEGylation has been shown to increase the half-life of drugs and decrease their immunogenicity. The hydroxyl group is a versatile functional group that can participate in various chemical reactions, such as esterification, etherification, and oxidation.
N3-PEG-OH can be used in pharmaceutical research and development to create various drug delivery systems, such as liposomes, micelles, and dendrimers. The hydrophilic PEG component improves the stability and solubility of these drug carriers, while the azide group allows for site-specific bioconjugation with various biomolecules, such as antibodies, peptides, and proteins.
N3-PEG-OH
Cat# | Name | Structure | Pricing |
---|---|---|---|
AP15145 | N3-PEG-OH, MW 3.4K | Pricing | |
AP15146 | N3-PEG-OH, MW 10K | Pricing |