THAL-SNS-032 is a selective CDK9 degrader PROTAC comprising the cyclin-dependent kinase inhibitor SNS 032 conjugated to the cereblon E3 ligase ligand thalidomide. THAL-SNS-032 can induce complete degradation of Cdk9 in MOLT4 cells at 250 nM. Thereby inhibiting the proliferation of leukemia cell lines.
THAL-SNS-032
| Cat# | Name | Structure | Pricing |
|---|---|---|---|
| AP14679 | THAL-SNS-032 | Pricing |
