Ald-Ph-PEG-PFP

Ald-Ph-PEG-PFP is a class of molecules used in pharmaceutical research and development as a versatile platform for drug delivery. The name Ald-Ph-PEG-PFP refers to the functional groups present in the molecule, which include an aldehyde (Ald), a phenyl group (Ph), a polyethylene glycol (PEG) chain, and a pentafluorophenyl (PFP) ester. The aldehyde group allows for conjugation to various biomolecules, such as proteins or antibodies, while the PEG chain provides water solubility and helps to prolong circulation time in vivo. The PFP ester group can be used for drug conjugation, as well as for crosslinking the molecule to form nanoparticles. Ald-Ph-PEG-PFP has shown promise in a range of drug delivery applications, including targeted delivery to cancer cells, gene delivery, and immunotherapy.