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Fmoc-NH-PEG-acid is a versatile compound commonly used in drug research and development. This compound belongs to the class of PEGylated amino acids, which are widely used as linkers, spacers, or building blocks in the synthesis of bioconjugates, such as peptides, proteins, and drugs.

The functional groups of Fmoc-NH-PEG-acid include a carboxylic acid (-COOH) and a fluorenylmethyloxycarbonyl (Fmoc) protected amino group (-NH-Fmoc) attached to a polyethylene glycol (PEG) chain. The carboxylic acid group can participate in various chemical reactions, such as amidation, esterification, and coupling reactions, while the Fmoc-protected amino group can be selectively deprotected under mild basic conditions to expose the free amino group (-NH2).

The use of Fmoc-NH-PEG-acid has been well-documented in drug research and development. It has been utilized as a linker to conjugate drugs to targeting moieties, such as antibodies, peptides, or aptamers, to enhance their specificity and efficacy. Moreover, PEGylation of drugs using Fmoc-NH-PEG-acid has been shown to improve their pharmacokinetic and pharmacodynamic properties, such as solubility, stability, and bioavailability.

Fmoc-NH-PEG-acid

Cat# Name Structure M.W. Purity Pricing
AP10334Fmoc-NH-PEG1-acid355.39≥95% Pricing
AP10335Fmoc-NH-PEG2-acid399.44≥95% Pricing
AP10336Fmoc-NH-PEG3-acid443.49≥95% Pricing
AP11098Fmoc-NMe-PEG3-acid457.52≥95% Pricing
AP10337Fmoc-NH-PEG4-acid487.54≥95% Pricing
AP11099Fmoc-NMe-PEG4-acid501.58≥95% Pricing
AP10338Fmoc-NH-PEG5-acid531.60≥95% Pricing
AP10339Fmoc-NH-PEG6-acid575.65≥95% Pricing
AP10340Fmoc-NH-PEG7-acid619.70≥95% Pricing
AP10341Fmoc-NH-PEG8-acid663.75≥95% Pricing
AP10342Fmoc-NH-PEG9-acid707.81≥95% Pricing
AP10343Fmoc-NH-PEG10-acid751.86≥95% Pricing
AP10344Fmoc-NH-PEG11-acid795.91≥95% Pricing
AP10345Fmoc-NH-PEG12-acid839.96≥95% Pricing
AP10346Fmoc-NH-PEG15-acid972.12≥95% Pricing
AP10347Fmoc-NH-PEG16-acid1016.17≥95% Pricing
AP10348Fmoc-NH-PEG19-acid1148.33≥95% Pricing
AP10349Fmoc-NH-PEG20-acid1192.39≥95% Pricing
AP11097Fmoc-NH-PEG23-acid1324.56≥95% Pricing
AP10350Fmoc-NH-PEG24-acid1368.60≥95% Pricing
AP10351Fmoc-NH-PEG25-acid1412.65≥95% Pricing
AP10352Fmoc-NH-PEG28-acid1544.81≥95% Pricing
AP10353Fmoc-NH-PEG30-acid1632.93≥95% Pricing
AP10354Fmoc-NH-PEG36-acid1897.23≥95% Pricing

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