Other DOTA-PEG reagents are a type of chelating agent used in peptide and drug conjugation experiments. They are used to attach molecules to peptides, proteins, and other molecules in order to increase their solubility, stability, and bioavailability. Other DOTA-PEG reagents are composed of a polyethylene glycol (PEG) backbone with a DOTA chelating group attached to the end. The chelating group allows for the attachment of molecules such as metals, fluorophores, and drugs to the PEG backbone.