Folate(folic acid) PEG linker is a PEG reagents with folic acid functional group.
Folate receptor is a membrane-bound protein that has high affinity for folic acid. This receptor serves as a receptor-mediated transport system of folic acid into cancer and cells associated with inflammation (e.g., macrophages). As a basic component of cell metabolism in both the synthesis of DNA and proteins, Folate is believed to be essential for maintaining elevated metabolic process. unlike most normal cells in the body have little or no high affinity folate receptor alpha, folate receptor is highly expressed in cancer cells. Because of these attributes, folate based drug delivery, imaging systems, and diagnostic systems are in various stages of development worldwide.
AxisPharm is the worldwide leading provider of folate related linkers for crosslinking technologies. We have the largest folate peg linkers in stock to facilitate the folate receptor related research.