APDye Fluor 800

APDye Fluor 800 – Premium Near-Infrared Fluorophore

Overview: APDye Fluor 800 is a state-of-the-art near-infrared (NIR) dye designed for advanced imaging applications. This novel space-shielding NIR cyanine heptamethine dye is invisible to the naked eye, but provides exceptional fluorescence for infrared imaging systems. Its unique design features PEG shielding arms that enhance its brightness and reduce unwanted bimolecular interactions.

Key Features:

• Fluorescence Properties:
  • Color: Near-infrared (NIR)
  • Brightness: Significantly increased fluorescence brightness due to shielding PEG arms
  • Visibility: Invisible to the naked eye, optimized for NIR imaging systems
• Chemical Design:
  • Shielding Arms: Two PEG arms shield the heptamethine fluorochrome on both sides, preventing undesired bimolecular associations and enhancing fluorescence brightness.
  • Spectral Similarity: Comparable to other near-infrared dyes like Alexa Fluor™ 790, IRDye™ 800, and DyLight 800.
• Applications:
  • Infrared Imaging: Ideal for high-resolution NIR imaging in various research and clinical applications.
  • Fluorescence Detection: Provides clear, bright signals in fluorescence assays and imaging systems.

Benefits:

• Enhanced Brightness: The unique shielding design results in superior fluorescence brightness.
• Reduced Interference: PEG shielding minimizes unwanted bimolecular interactions, leading to more accurate imaging.
• Compatibility: Works seamlessly with infrared imaging systems and is comparable to other leading NIR dyes.

Summary: APDye Fluor 800 is an advanced near-infrared fluorophore that offers exceptional brightness and reduced interference for superior imaging results. Its innovative design with shielding PEG arms makes it an excellent choice for a variety of infrared imaging applications. Whether you’re conducting research or clinical imaging, APDye Fluor 800 provides reliable, high-performance fluorescence.

Ref:

Caiping Ding, Tianbing Ren, Near infrared fluorescent probes for detecting and imaging active small molecules, Coordination Chemistry Reviews,
Volume 482, 2023, 215080.