Click Chemistry Reagents: Your Comprehensive Guide
Click chemistry reagents are vital for precise chemical synthesis and bioconjugation. They are widely used in pharmacology, biological research, and drug development due to their rapid reaction rates, high specificity, and minimal byproducts.
Product Categories
1. Azides
click chemistry tool - azide
Description: Azides (-N₃) are key for click chemistry, reacting with alkynes to form stable triazole linkages. Ideal for tagging and functionalizing biomolecules and small molecules.
Examples:
- 1-Azido-2-propanol: Tags alcohol-containing compounds.
- 5-Azido-2-nitrobenzoic acid: Coupling with carboxylic acids.
2. Alkynes
click chemistry tool - allkyne
Description: Alkynes (-C≡C-) react with azides to form triazole rings, essential for bioconjugation and materials science.
Examples:
- Propargyl Alcohol: Versatile functional alkyne.
- Cyclooctyne: Strained alkyne for copper-free click chemistry.
3. Cyclooctynes
click chemistry tool - BCN
Description: Cyclooctynes enable copper-free click reactions and are perfect for high-efficiency bioconjugation.
Examples:
- DIBAC: For rapid bioorthogonal reactions.
- DBCO (Dibenzocyclooctyne): Ideal for bioconjugation and imaging.
4. Tetrazines
Click chemistry tool Tetrazine
Description: Tetrazines react with strained alkynes to form stable conjugates, useful for rapid and efficient bioconjugation.
Examples:
- Tetrazine-PEG-COOH: Links with various biomolecules.
- Tetrazine-Rhodamine: For fluorescent labeling.
5. TCO (Trans-Cyclooctene)
Click chemistry tool TCO
Description: TCO reacts with tetrazines to form stable conjugates, valuable for bioconjugation and imaging.
Examples:
- TCO-PEG-Alkylamine: Links with biomolecules.
- TCO-Fluorescein: For fluorescent tagging.
6. Click Reaction Ligands
Description: These specialized compounds enhance click chemistry reactions, improving efficiency and specificity.
Examples:
- Click Reaction Ligand-PEG: Versatile linking platform.
- Ligand-Functionalized Probes: Optimizes click reactions.
7. Fluorescent Click Chemistry Probes
Description: Combine click chemistry with fluorescence for sensitive imaging and tracking.
Examples:
- Fluorescein-azide: Provides bright fluorescence.
- Rhodamine-alkyne: Ideal for tracking studies.
8. Custom Click Chemistry Solutions
Description: Tailored reagents and kits for specialized research needs.
Examples:
- Custom Click Chemistry Kits: Selection of reagents for specific applications.
- Bespoke Reagents: Custom synthesis of click chemistry tools.
Why Choose AxisPharm?
- Extensive Selection: Over 600 high-purity click chemistry tools, including azides, alkynes, DBCO, TCO, tetrazines, BCN, and more.
- High Quality: Reliable and reproducible results with top-notch purity.
- Efficiency: Fast reactions, high yields, and minimal byproducts.
- Versatility: Perfect for bioconjugation, fluorescence spectrometry, cell imaging, and drug delivery.
Explore our click chemistry reagents to find the perfect tools for your research. For personalized recommendations or to place an order, contact us today!
Ref:
- Maujean, T., Ramanoudjame, S.M., Riché, S., Le Guen, C., Boisson, F., Muller, S., Bonnet, D., Gulea, M. and Marchand, P., 2024. Hetero-Diels–Alder and CuAAC Click Reactions for Fluorine-18 Labeling of Peptides: Automation and Comparative Study of the Two Methods. Molecules, 29(13), p.3198.
