PLGA-di-hydroxyl, MW 10K

PLGA-di-hydroxyl (PLGA-diol), MW 10K is a medium-molecular-weight linear biodegradable copolymer functionalized with hydroxyl groups at both termini. Synthesized from D,L-lactide and glycolide monomers with tunable LA/GA ratios (50:50, 65:35, 75:25, 85:15 and custom ratios), this bifunctional polyester exhibits excellent biocompatibility and programmable degradation performance suitable for diverse biomedical scenarios. The symmetric dual-terminal hydroxyl structure offers abundant reactive sites for secondary functionalization, enabling efficient fabrication of advanced block copolymers, crosslinkable hydrogel networks, and customized polymer conjugates. Its in-vivo degradation metabolites (lactic acid and glycolic acid) are naturally metabolized by human tissues, ensuring low cytotoxicity and high biological safety. As a versatile intermediate polymer, 10K PLGA-diol is extensively adopted for controlled-release carrier construction, nanoparticle engineering, and functional biomaterial development in pharmaceutical and tissue engineering research.