PLGA-di-hydroxyl, MW 40K

PLGA-di-hydroxyl (PLGA-diol), MW 40K is an ultra-high molecular weight linear biodegradable polyester with hydroxyl functional groups capped at both molecular ends. Synthesized from D,L-lactide and glycolide monomers, the polymer supports multiple standard lactide-glycolide ratios of 50:50, 65:35, 75:25, 85:15, as well as fully customized ratio configurations to meet diverse experimental needs. Distinguished from low and medium molecular weight counterparts, this 40K PLGA-diol possesses ultra-long molecular chains, outstanding mechanical strength, excellent structural rigidity and an extremely slow in-vitro and in-vivo degradation cycle. Its symmetric double-terminal hydroxyl groups retain good chemical reactivity, supporting advanced modification such as high-molecular block copolymer synthesis, high-strength hydrogel crosslinking, and high-stability polymer conjugate preparation. With biocompatible degradation metabolites that can be naturally cleared by biological tissues, the material delivers superior biosafety. It is uniquely suited for the development of ultra-long sustained-release drug delivery systems, high-toughness biodegradable tissue scaffolds, stable long-cycle nanoparticle carriers and high-performance biomedical polymer materials.