PLGA-di-hydroxyl, MW 40K is a biodegradable PLGA polymer featuring terminal hydroxyl functionality and an approximate molecular weight of 40 kDa where its hydroxyl end groups specifically support further derivatization, drug delivery, polymer modification, and biomaterial applications.
Key Features and Benefits
- Hydroxyl Functionalization: Provides terminal hydroxyl groups for further derivatization and conjugation.
- MW 40K: Moderate molecular weight supports polymer processing and sustained-release formulations.
- Biodegradable: PLGA degrades into lactic acid and glycolic acid under physiological conditions.
- Difunctional Polymer: Hydroxyl groups at both ends enable versatile polymer modification strategies.
- Versatile Platform: Suitable for preparing functional polymers, particles, conjugates, and biodegradable materials.
Applications
- Polymer Modification: Hydroxyl groups provide sites for further chemical functionalization.
- Drug Delivery: Supports biodegradable controlled and sustained-release formulations.
- Nanoparticles: Used to prepare biodegradable polymeric nanoparticles and drug carriers.
- Bioconjugation: Can be derivatized with reactive groups for subsequent biomolecule attachment.
- Biomaterials: Suitable for biodegradable matrices, coatings, scaffolds, and related research.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to minimize premature hydrolysis and polymer degradation.
PLGA-di-hydroxyl, MW 40K combines biodegradable PLGA with terminal hydroxyl functionality, providing an especially versatile polymer platform for drug delivery, chemical derivatization, nanoparticle formulation, and biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.