PLGA-di-hydroxyl, MW 5K is a low-molecular-weight biodegradable PLGA polymer featuring terminal hydroxyl functionality where its hydroxyl end groups and ~5 kDa molecular weight support chemical derivatization, drug delivery, polymer modification, and biomaterial applications.
Key Features and Benefits
- Hydroxyl Functionalization: Provides terminal hydroxyl groups for further derivatization and conjugation.
- MW 5K: Low molecular weight supports efficient polymer processing and flexible formulation development.
- Biodegradable: PLGA degrades into lactic acid and glycolic acid under physiological conditions.
- Difunctional Polymer: Hydroxyl groups at both ends enable versatile polymer modification strategies.
- Versatile Platform: Suitable for preparing functional polymers, particles, conjugates, and biodegradable materials.
Applications
- Polymer Modification: Hydroxyl groups provide sites for further chemical functionalization.
- Drug Delivery: Supports biodegradable drug delivery and controlled-release formulations.
- Nanoparticles: Used to prepare biodegradable polymeric nanoparticles and drug carriers.
- Bioconjugation: Can be derivatized with reactive groups for subsequent biomolecule attachment.
- Biomaterials: Suitable for biodegradable matrices, coatings, and related material research.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to minimize premature hydrolysis and polymer degradation.
PLGA-di-hydroxyl, MW 5K combines low molecular weight, biodegradable PLGA, and terminal hydroxyl functionality, specifically providing a versatile platform for drug delivery, chemical derivatization, polymer modification, and biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.