8-arm-PLGA-OH, MW 10K is a biodegradable multi-arm PLGA polymer with eight hydroxyl-functionalized arms and an approximate molecular weight of 10 kDa where its branched architecture specifically supports polymer modification, drug delivery, crosslinking, and advanced biomaterial applications.
Key Features and Benefits
- 8-Arm Architecture: Provides a branched polymer structure with multiple functional arms.
- Hydroxyl Functionalization: Offers terminal hydroxyl groups for derivatization and conjugation.
- MW 10K: Low molecular weight specifically supports efficient processing and flexible formulation development.
- Biodegradable: PLGA segments degrade into lactic acid and glycolic acid under physiological conditions.
- Multivalent Platform: Multiple hydroxyl groups enable crosslinking and multifunctional polymer modification.
Applications
- Drug Delivery: Supports biodegradable controlled-release and carrier systems.
- Polymer Modification: Hydroxyl groups provide multiple sites for chemical derivatization.
- Crosslinking: Enables preparation of crosslinked polymer networks and biodegradable matrices.
- Nanoparticles: Suitable for development of branched PLGA-based particles and drug carriers.\
- Biomaterials: Used in hydrogels, scaffolds, coatings, and tissue engineering research.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to minimize premature hydrolysis and polymer degradation.
8-arm-PLGA-OH, MW 10K combines a branched eight-arm architecture with terminal hydroxyl functionality, specifically providing a versatile biodegradable platform for drug delivery, crosslinking, polymer modification, and biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.