PCL-PEG-FITC, MW x 2K, n 5K is a fluorescently labeled amphiphilic block copolymer composed of poly(ε-caprolactone) (PCL) and polyethylene glycol (PEG) with fluorescein (FITC) functionality. This grade combines approximately 2K PCL with 5K PEG, providing a strongly PEG-rich architecture for aqueous stabilization while enabling fluorescence-based detection and tracking.
Key Features and Benefits
- Amphiphilic Copolymer: Combines hydrophobic PCL with hydrophilic PEG for polymer assembly and drug delivery research.
- PCL MW 2K: Provides a biodegradable hydrophobic segment specifically for core formation and incorporation of hydrophobic compounds.
- PEG MW 5K: Provides a dominant hydrophilic segment specifically for aqueous compatibility and steric stabilization.
- PEG-Rich Architecture: The 5:2 PEG-to-PCL molecular weight ratio favors hydrophilic surface character and stabilization of polymer assemblies.
- Fluorescent Label: FITC provides fluorescein-based fluorescence for visualization and detection of labeled polymer systems.
- Optical Tracking: Enables fluorescence-based monitoring of polymer assemblies, nanoparticles, and biomaterial distribution.
Applications
- Fluorescent Nanoparticles: Supports preparation and visualization of fluorescently labeled nanoparticles and micelles.
- Drug Delivery Research: Enables fluorescence-based tracking of polymeric drug delivery systems.
- Cellular Studies: Supports investigation of cellular association, uptake, and localization of labeled polymer assemblies.
- Bioimaging Research: Provides fluorescent labeling for microscopy and other fluorescence-based analytical techniques.
- Biomaterial Research: Supports visualization and characterization of PCL-PEG-based biomaterial systems.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry conditions and protected from light.
- Handling: Minimize exposure to light, moisture, and excessive heat to preserve polymer integrity and fluorescence performance.
PCL-PEG-FITC, MW x 2K, n 5K combines a short biodegradable PCL block with a dominant PEG segment and fluorescein functionality and specifically supports stabilized fluorescent polymer assemblies, nanoparticle tracking, drug delivery studies, and biomaterial imaging.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.