PCL-PEG-FITC, MW x 5K, n 2K is a fluorescent amphiphilic block copolymer composed of poly(ε-caprolactone), polyethylene glycol, and a fluorescein isothiocyanate (FITC) fluorescent label. The 5K PCL block provides a hydrophobic domain for self-assembly and cargo incorporation, while the 2K PEG block provides surface stabilization and FITC enables fluorescence-based visualization and tracking.
Key Features and Benefits
- Fluorescent Amphiphilic Copolymer: Integrates hydrophobic PCL, hydrophilic PEG, and an FITC fluorescent label.
- PCL MW 5K: Provides a biodegradable hydrophobic segment for nanoparticle or micelle core formation and hydrophobic cargo incorporation.
- PEG MW 2K: Provides a hydrophilic segment for aqueous compatibility, surface hydration, and interfacial stabilization.
- PCL-Rich Architecture: The 5:2 PCL-to-PEG molecular weight ratio favors hydrophobic core formation while retaining PEG surface functionality.
- FITC Fluorescence: Provides green fluorescence suitable for visualization and fluorescence-based tracking of polymer-containing formulations.
- Carrier Tracking: Enables investigation of nanoparticle localization, cellular uptake, intracellular trafficking, and polymer distribution.
Applications
- Fluorescent Nanoparticles: Preparation of FITC-labeled polymeric nanoparticles, micelles, and related assemblies.
- Drug Delivery Research: Enables fluorescence-based tracking of polymeric carriers containing hydrophobic compounds.
- Cellular Uptake Studies: Supports fluorescence microscopy and evaluation of polymer or nanoparticle internalization.
- Biodistribution Research: Enables tracking of fluorescent polymer carriers in suitable experimental models.
- Biomaterial Imaging: Supports visualization of polymer localization and transport in biomaterial and tissue-engineering studies.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry, light-protected conditions.
- Handling: Protect from light, moisture, and excessive heat to preserve polymer integrity and fluorescence performance.
This product combines a PCL-rich amphiphilic architecture with FITC fluorescence and specifically supports traceable polymeric carriers for nanoparticle imaging, cellular uptake, localization, and hydrophobic drug delivery research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.